These tumors are a mucosal form of basal cell carcinoma.
Commonly referred to as a form of epulis, ameloblastoma relates to the cell type of origin, odontogenic epithelial cells, and acanthomatous refers to the spiny shape of epithelial cells within these tumors.
These tumors usually invade the local bone of the mandible and are commonly located in the rostral aspect of the lower jaw in medium and large breed dogs.
Affected dogs usually present for reasons of dysphagia, bleeding gums or the condition is noticed during routine clinical examination. Radiographic or CT examination usually shows bone lysis.
Diagnosis often requires biopsy sampling and histological analysis.
A differential diagnosis would include squamous cell carcinoma (most prevalent), fibroma and fibrous hyperplasia (rostral maxilla), dentigerous cyst, bone cysts, peripheral giant cell granulomas and melanoma.
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