Amikacin is a broad-spectrum bactericidal aminoglycoside antimicrobial drug similar to gentamycin.
Amikacin works by binding to the bacterial 30S ribosomal subunit, causing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to its growth.
Side-effects with use of this drug are similar to other aminoglycosides and include ototoxicity and renal damage.
Recommended dose rate in dogs is 20 mg/kg, given subcutaneously.
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