Ampicillin

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Ampicillin is a synthetic penicillin antimicrobial drug similar in activity to amoxicillin, bactericidal against Gram-positive and some Gram-negative bacteria[1].

In canine medicine, this drug is used to treat cystitis, otitis media and bacterial meningitis.

Resistance is commonly reported with Salmonella spp and Escherichia coli[2].

The use of this drug should be reserved for documented cases where culture and sensitivity have confirmed its suitability[3].

Recommended dose rate in dogs is 20 - 60 mg/kg given orally every 8 - 12 hrs.

References

  1. Awji EG et al (2012) The in vitro activity of 15 antimicrobial agents against bacterial isolates from dogs. J Vet Med Sci 74(8):1091-1094
  2. Leonard EK et al (2012) Comparison of antimicrobial resistance patterns of Salmonella spp. and Escherichia coli recovered from pet dogs from volunteer households in Ontario (2005-06). J Antimicrob Chemother 67(1):174-181
  3. Wayne A et al (2011) Therapeutic antibiotic use patterns in dogs: observations from a veterinary teaching hospital. J Small Anim Pract 52(6):310-318
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