Species which are pathogenic to dogs include:
- Anaplasma phagocytophilum (formerly Ehrlichia phagocytophila)
- Anaplasma bovis
- Anaplasma platys
Clinical signs associated with anaplasmosis include lethargy, anorexia, fever arthropathy, anemia, and gastrointestinal signs such as abdominal pain, diarrhea and vomiting. Lymphadenopathy, splenomegaly, neurologic dysfunction, retinal detachment and epistaxis have also been reported. Many subclinical infections without clinical signs are also possible.
Hematological changes include thrombocytopenia, morulae in neutrophils, anemia, leukopenia, eosinopenia, lymphopenia, and monocytosis.
Treatment involves use of doxycycline (5 mg/kg orally every 12 hours) or imidocarb (single injection at 1.5 mg/kg SC).
Prevention is critical to eradication of tick-borne diseases in endemic regions, and control of tick populations on dogs by preventive topical fipronil, amitraz or other acaricides is important.
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