Budesonide

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Budesonide is a medium-acting corticosteroid similar to betamethasone.

This drug is indicated for treatment of bronchitis[1] as an inhaled drug and orally for treatment of irritable bowel disease[2] and as a topical drug for treatment of atopy[3].

The main side-effects with this drug is suppression of the pituitary-adrenal function[4].

Recommended dose rate in dogs is 3 mg/m2 given orally once daily.

References

  1. Melamies M et al (2012) Endocrine effects of inhaled budesonide compared with inhaled fluticasone propionate and oral prednisolone in healthy Beagle dogs. Vet J 194(3):349-353
  2. Pietra M et al (2013) Plasma concentrations and therapeutic effects of budesonide in dogs with inflammatory bowel disease. Am J Vet Res 74(1):78-83
  3. Olivry T & Bizikova P (2013) A systematic review of randomized controlled trials for prevention or treatment of atopic dermatitis in dogs: 2008-2011 update. Vet Dermatol 24(1):97-117
  4. Stroup ST et al (2006) Effects of oral administration of controlled-ileal-release budesonide and assessment of pituitary-adrenocortical axis suppression in clinically normal dogs. Am J Vet Res 67(7):1173-1178
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