Calcareous degeneration

From Dog

Calcareous degeneration is an ophthalmic disease of dogs characterized by end-stage corneal calcium or lipid mineralization associated with chronic ulcerative keratitis and corneal dystrophy[1].

Calcareous and lipid degeneration may be either primary or secondary, associated with systemic diseases such as primary hyperlipidemia, hyperlipidemia associated with hyperadrenocorticism and hypothyroidism[2][3].


  1. Clerc B (1983) Corneal pathology in the cat and dog. J Fr Ophtalmol 6(8-9):731-747
  2. Laus JL et al (2002) Combined corneal lipid and calcium degeneration in a dog with hyperadrenocorticism: a case report. Vet Ophthalmol 5(1):61-64
  3. Sansom J & Blunden T (2010) Calcareous degeneration of the canine cornea. Vet Ophthalmol 13(4):238-243