From Dog

Chlorpromazine is an antiemetic drug which acts as a dopaminergic D2 receptor antagonist similar to acepromazine.

This drug has been used as a pre-anesthetic sedative[1] and for motion sickness but is less effective than other drugs such as maropitant[2].

Recommended dose rate in dogs is 0.5 mg/kg given intramuscularly every 8 - 12 hours.


  1. Luna SP et al (2004) Effects of four anaesthetic protocols on the neurological and cardiorespiratory variables of puppies born by caesarean section. Vet Rec 154(13):387-389
  2. Sedlacek HS et al (2008) Comparative efficacy of maropitant and selected drugs in preventing emesis induced by centrally or peripherally acting emetogens in dogs. J Vet Pharmacol Ther 31(6):533-537