Clonazepam is a benzodiazepine drugs with anxiolytic, anticonvulsant, muscle relaxant, sedative, and hypnotic properties.
After oral administration, clonazepam is rapidly absorbed, but due to high protein-binding following uptake, has bioavailability poor and variable responses pharmacokinetically.
Physical dependence occurs with this drug in dogs that have been prescribed long courses (>6 weeks) and should be used with caution and withdrawn slowly.
Recommended dose rate in dogs is 0.5 mg/kg given orally every 8 - 12 hours.
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