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These yeasts are normally found in the gastrointestinal lining of dogs and cats, but a higher percentage are found in domestic and feral rabbits, guinea pigs, and chinchillas.
Species which are pathogenic to dogs include:
- Cyniclomyces guttulatus 
Diseases associated with this yeast are rare, but an association with inflammatory bowel disease and choloecystitis have been reported.
Most dogs present with vomiting and diarrhea. On cases of cholecystitis, signs referable to acute hepatitis and cholecystitis are observed.
Diagnosis is based on isolation and identification of yeast in feces or viscera under light microscopy.
Recommended treatment is nystatin, given orally at 500,000 IU/kg daily for 4 - 7 days.
- Flausino G et al (2012) Isolation and Characterization of Cyniclomyces guttulatus (Robin) Van Der Walt and Scott, 1971 in Dogs in Brazil. Curr Microbiol 65(5):542-546
- Zierdt CH et al (1988) Cyniclomyces guttulatus (Saccharomycopsis guttulata) - culture, ultrastructure and physiology. Antonie Van Leeuwenhoek 54(4):357-366
- Gjerde, B et al (2009) A Cyniclomyces gutitulatus-like yeast associated with recurrent gastroenteritis in a dog. Norsk Veterinærtidsskrift 121(6):507-510
- Dijkstra M et al (2010) Protein-losing enteropathy in Rottweilers. Tijdschr Diergeneeskd 135(10):406-412
- Neel JA et al (2006) Gallbladder aspirate from a dog. Vet Clin Pathol 35(4):467-470
- Peters S & Houwers DJ (2009) A cat with diarrhoea associated with the massive presence of Cyniclomyces guttulatus in the faeces. Tijdschr Diergeneeskd 134(5):198-199