Fampridine (4-Aminopyridine) is an isomeric derivative of pyridine which blocks potassium channels, prolonging action potentials and thereby increasing neurotransmitter release at the neuromuscular junction.
It is a lipid-soluble drug which readily crosses the blood-brain barrier.
It is used primarily for neurological signs associated with CNS disease due to its ability to restore conduction to demyelinated axons and improve neurological function.
Recommended dose rate is 0.1 - 0.5 mg/kg given once daily.
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