From Dog
Histopathological appearance of an odontogenic fibroma[1]
Splenic fibroma in a dog[2]

Fibroma is a benign neoplasm of the canine connective tissue.

These tumors are discrete, generally cellular proliferations of dermal fibroblasts and are usually non-invasive or metastatic.

Cutaneous fibromas are commonly reported in Doberman, Boxer and Golden Retriever breeds, mainly occurring on the head, mouth and extremities.

Variants include keloid fibroma, ameloblastic fibroma and desmoid-type fibromatosis[3].

Odontogenic ameloblastic fibromas are commonly reported in the oral cavity[4], external auditory canal[5], cranium[6]kidney, spleen[7], penis[8] and vagina[9].

Diagnosis is usually based on histological examination of biopsied material. Histologically, they resemble collagenous nevi or cutaneous tags.

A differential diagnosis would include dermoid cyst, acanthomatous ameloblastoma, fibrosarcoma, mast cell tumor and lipoma[10].

Surgical extirpation is usually required as they can grow quite large, and excision is usually curative.

The adjunct use of aglepristone has also been trialed successfully with vaginal fibromas.


  1. Nah KS (2011) Central odontogenic fibroma: a case report. Imaging Sci Dent 41(2):85-88
  2. Rahal SC et al (1996) Splenic fibroma in a dog. Can Vet J 37(12):740-741
  3. Cook JL et al (1998) Infantile desmoid-type fibromatosis in an Akita puppy. J Am Anim Hosp Assoc 34(4):291-294
  4. Boehm B et al (2011) Odontogenic tumours in the dog and cat. Tierarztl Prax Ausg K Kleintiere Heimtiere 39(5):305-312
  5. Park JK et al (2010) Fibroma with osseous metaplasia of external auditory canal in a dog. J Vet Diagn Invest 22(4):635-638
  6. Bordelon JT & Rochat MC (2007) Use of a titanium mesh for cranioplasty following radical rostrotentorial craniectomy to remove an ossifying fibroma in a dog. J Am Vet Med Assoc 231(11):1692-1695
  7. Rahal SC et al (1996) Splenic fibroma in a dog. Can Vet J 37(12):740-741
  8. Mirkovic TK et al (2004) Urinary obstruction secondary to an ossifying fibroma of the os penis in a dog. J Am Anim Hosp Assoc 40(2):152-156
  9. Rollón E et al (2008) Effects of aglepristone, a progesterone receptor antagonist, in a dog with a vaginal fibroma. J Small Anim Pract 49(1):41-43
  10. Pakhrin B et al (2007) Retrospective study of canine cutaneous tumors in Korea. J Vet Sci 8(3):229-236