Glargine is a long-acting synthetic insulin used for the treatment of canine diabetes mellitus.
Glargine is a synthetic insulin analogue and is produced using recombinant DNA technology utilizing Escherichia coli.
Recommended dose rate is 0.25 - 0.5 U/kg as a starting dose.
Glargine (Lantus) must not be diluted or mixed as this affects the peak effect.
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- Mori A et al (2008) Comparison of time-action profiles of insulin glargine and NPH insulin in normal and diabetic dogs. Vet Res Commun 32(7):563-573
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- Hess, R & Ward. C (2000) Effect of insulin dosage on glycaemic response in dogs with diabetes mellitus: 221 cases (1993-1998). J Am Vet Med Assoc 216:217