Lentiginosis profusa

From Dog

Lentiginosis profusa is a dermatological abnormality of dogs characterized by excess numbers of superficial lentigines (singular: lentigo).

A predisposition has been reported in the Pug.

Macroscopically the lentigines appear as small black pigmented macules produced by herplastic melanocytes. They measure up to 10 mm in diameter and commonly occur in the skin of the ventral parts of the body, inguinal region, prepuce and nipples[1].

Skin biopsies usually reveal localised acanthosis and hyperkeratosis with prominent rete ridges and epidermal hyperpigmentation[2].

Lentigonsis profusa are rarely cause for concern but should be monitored regularly for malignant transformation into melanocytomas[3].


  1. Kraft I & Frese K (1976) Lentigo-like proliferations of the teat epithelium in the dog. Zentralbl Veterinarmed A 23(3):234-247
  2. Van Rensburg IB & Briggs OM (1986) Pathology of canine lentiginosis profusa. J S Afr Vet Assoc 57(3):159-161
  3. Coyner K & Loeffler D (2012) Topical imiquimod in the treatment of two cutaneous melanocytomas in a dog. Vet Dermatol 23(2):145-149