Miconazole

From Dog

Miconazole is an imidazole antifungal agent used primarily in lotions for topical therapy such as ringworm and Malassezia spp[1] infections.

This product has shown to be superior to other topical antimicrobials such as benzoyl peroxide, and equal in efficacy to chlorhexidine.

Because this drug also has antimicrobial activity, it has shown effectiveness against meticillin-resistant Staphylococcus aureus and meticillin-resistant Staphylococcus pseudintermedius[2].

It is also available as an ear formulation for treatment of otitis externa and for keratomycosis[3].

References

  1. Mueller RS et al (2012) A review of topical therapy for skin infections with bacteria and yeast. Vet Dermatol 23(4):330-341
  2. Boyen F et al (2012) In vitro antimicrobial activity of miconazole and polymyxin B against canine meticillin-resistant Staphylococcus aureus and meticillin-resistant Staphylococcus pseudintermedius isolates. Vet Dermatol 23(4):381-385
  3. Ben-Shlomo G et al (2010) Curvularia keratomycosis in a dog. Vet Ophthalmol 13(2):126-130