From Dog

Mitoxantrone is an anthracenedione antineoplastic agent.

This drug has been used for treatment of anal sac adenocarcinoma in conjunction with radiation therapy.

Recommended dose in dogs is 5 mg/m2 every 3 weeks for five treatments[1].


  1. Turek MM et al (2003) Postoperative radiotherapy and mitoxantrone for anal sac adenocarcinoma in the dog: 15 cases (1991-2001). Vet Comp Oncol 1(2):94-104