Nasal depigmentation

From Dog

Nasal depigmentation ('Dudley nose') is a common non-pathogenic disorder of the nasal planum of dogs characterized by depigmentation of skin.

A genetic predisposition has been noted in a number of breeds including the Australian Shepherd, Afghan, Alaskan Malamute, Bernese Mountain Dog, Doberman Pinscher, German Shepherd (White), Golden Retriever, Irish Setter, Labrador Retriever (Yellow), German Short-haired Pointer, Miniature Poodle, Samoyed and Siberian Husky.

The precise cause of this loss of pigment and colour change is not known but it is possibly a form of vitiligo. Presumably the condition is intimately linked to pineal gland and/or melanocyte activity.

In some individuals the amount of pigment present may change from time to time, in others it remains depigmented[1].

A differential diagnosis would include uveodermatologic syndrome and lupus erythematosus.

There is no recognized therapy for this condition which is otherwise not harmful to the affected patient.