Panniculitis refers to granulomatous inflammation of subcutaneous fat.
Small, firm, painful nodules protrude through the skin usually on the flanks of dogs and are unlikely to be cancerous. A few of the nodules are mobile and some rupture and drain an oily brown or blood-tinged discharge. Scarring may occur in the area of the ruptured nodules, and a secondary Staphylococcus spp infection may be present after rupture.
Anorexia, depression, fever and lethargy may be present in dogs with multiple lesions.
This disease is commonly seen following trauma but has been associated with other diseases such as:
- Bacterial diseases
- Systemic lupus erythematosus
- Vitamin E deficiency
- Steroid-responsive meningitis-arteritis
- Sterile nodular panniculitis
- Dirofilaria repens
- Albanese F et al (2013) Nodular lesions due to infestation by Dirofilaria repens in dogs from Italy. Vet Dermatol 24(2):255-256