Pasteurella spp

From Dog

Pasteurella spp are a genus of zoonotic Gram-negative, facultatively anaerobic bacteria

Pasteurella are small coccobacilli that are primarily natural saprophytic inhabitants of the skin, oral flora and digestive tract of dogs[1], but can be primary pathogens with a predilection for anaerobic site and a tendency to pus formation. The bacterium spreads from dog to dog by aerosols.

These bacteria are of zoonotic importance due to common infections of humans through bite wounds and licking of open wounds, resulting in cellulitis or septicemia[2].

In dogs, they are associated with a wide range of diseases from otitis externa to rhinitis, orbital abscess[3], septic arthritis[4], osteomyelitis[5], pyothorax[6], meningitis[7] and systemic pasteurellosis in puppies[8], depending on the etiological agent.

Species which are pathogenic to dogs include:

Several virulence factors have been described in Pasteurella spp, particularly dermonecrotoxin[19] and leukotoxin[20] which have been isolated from P haemolytica.

In systemic pasteurellosis of young dogs, disease consist mainly of hemorrhagic septicemia and pneumonia, which is often fatal[21].

Diagnosis is based on bacterial culture and PCR assay identification of species[22].

Several decades of clinical experiences with Pasteurella and numerous in vitro studies indicate that penicillin is the best antimicrobial agent for the treatment of virtually all forms of infection[23].

This group of bacteria also show sensitivity to β-lactams, amoxycillin/clavulanate, metronidazole[24], chloramphenicol, gentamicin, cefovecin[25] and fluorquinolones such as ciprofloxacin and pradofloxacin[26].

Severe or partially responding infections may necessitate hospitalization and parenteral antimicrobial administration, along with surgical intervention.


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  2. Jüch M et al (2012) A 76-year-old dog owner with fever and dyspnea. Internist (Berl)' 53(9):1114-1118
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