Phenylpropanolamine is a partial α1-agonist drug with a low intrinsic activity and affinity, that acts on the urethral sphincter mechanism.
The reported success rate associated with this treatment ranges from 85% - 97% continence, but a decrease in urethral response associated with recurrence of incontinence can be observed after a prolonged administration of this drug.
Recommended dose rate in dogs is 1 - 1.5 mg/kg body weight two to three times daily.
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