S-Adenosylmethionine (SAMe), a common cosubstrate involved in methyl group transfers, is a glutathione replenisher.
It thus acts as a potent antioxidant and cytoprotective agent that protects cells from toxins and cell death.
S-Adenosylmethionine is also used as a supportive hepatic drug in dogs with cognitive deficit syndrome, reperfusion injuries, acetaminophen toxicity, chronic hepatitis, hepatitis, hepatic encephalopathy and portosystemic shunt.
The recommended dose rate in dogs is 20 - 30 mg/kg given orally as a daily dose.
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