Thrombocytosis in dogs refers to a marked elevation in circulating thrombocytes (platelets) > 9 x 1011/L.
This condition, which is invariably a secondary phenomenon to other diseases, is relatively common in dogs associated with splenic contraction observed during general anesthesia, or following splenectomy.
Pathological conditions which also cause thrombocytosis include:
- Inflammation - e.g. Lymphocytic-plasmacytic enteritis
- Immune-mediated hemolytic anemia
- Chronic allergies
- Iatrogenic - glucocorticoids, vincristine
Regardless of cause, affected dogs have a high risk of developing thromboembolism due to the increased hypercoagulable hemodynamic state.
- Neel JA et al (2012) Thrombocytosis: a retrospective study of 165 dogs. Vet Clin Pathol 41(2):216-222