Aspergillus spp are a commensal filamentous fungus found as part of the normal skin flora of dogs worldwide.
Species which are pathogenic to dogs include:
- Aspergillus fumigatus
- Aspergillus versicolor
- Aspergillus terreus
- Aspergillus deflectus (Neosartorya fischeri)
- Aspergillus ochraceus
A correlation between chronic inflammation and sequential development of tumors has to be considered, especially with nasal aspergillosis, as the risk of developing nasal granulomas is relatively high.
Diagnosis is based on clinical presentation and culture of the fungus in the laboratory. The fungus usually stains positively with periodic acid-Schiff and Grocott stains. Sensitive ELISA and PCR assays are available for establishing a definitive diagnosis.
Parenteral treatment is usually required with systemic involvement.
Itraconazole is the drug of choice, given for 5 - 6 months to effect elimination of fungal spores, but other drugs such as ketoconazole, itraconazole and enilconazole have also been trialed in dogs both parenterally and topically.
In dogs with localized pulmonary cavitations, a lobectomy is usually indicated.
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