Atenolol

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Atenolol is a selective β1 receptor antagonist (beta-blocker) similar to esmolol and is used for various hypertensive and arrhythmic diseases in dogs that predispose to development of congestive heart failure.

This drug is a negative chronotrope and inotrope and is thought to decrease myocardial oxygen demand while increasing time for ventricular and coronary filling[1].

It is primarily indicated for diseases such as subaortic stenosis, hypertrophic cardiomyopathy, atrial fibrillation, supraventricular tachycardia and premature ventricular complexes.

Recommended dose in dogs is 0.25 to 1.0 mg/kg once to twice daily. The total daily dose is often 6.25 to 25 mg/dog.

This drug is frequently given in combination with pimobendan.

References

  1. Kienle RD et al (1994) The natural clinical history of canine congenital subaortic stenosis. J Vet Intern Med 8:423–431