Difference between revisions of "Meglumine antimonite"

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Meglumine antimonate is a drug used for treatment of canine [[leishmaniasis]].
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Meglumine antimonate is a pentavalent antimonial drug used for treatment of canine [[leishmaniasis]].
  
Recommended dose rate in dogs is 5 - 30 ml/dog given intravenously or intramuscularly every 48 - 72 hrs.
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This drug may be given alone or in combination with [[allopurinol]]<ref>Miró G ''et al'' (2008) Canine leishmaniosis–new concepts and insights on an expanding zoonosis: Part two. ''Trends Parasitol'' '''24''':371–377</ref>.
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Recommended dose rate in dogs is 100 mg/kg subcutaneously once a day for twenty-eight consecutive days (3.3 mL/10 kg/day)<ref>Valladares JE ''et al'' (1997) Pharmacokinetics of liposome-encapsulated meglumine antimonate after intramuscular and subcutaneous administration in dogs. ''Am J Trop Med Hyg'' '''57(4)''':403-406</ref>.
  
 
==References==
 
==References==
 
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Latest revision as of 05:10, 26 April 2013

Meglumine antimonate is a pentavalent antimonial drug used for treatment of canine leishmaniasis.

This drug may be given alone or in combination with allopurinol[1].

Recommended dose rate in dogs is 100 mg/kg subcutaneously once a day for twenty-eight consecutive days (3.3 mL/10 kg/day)[2].

References

  1. Miró G et al (2008) Canine leishmaniosis–new concepts and insights on an expanding zoonosis: Part two. Trends Parasitol 24:371–377
  2. Valladares JE et al (1997) Pharmacokinetics of liposome-encapsulated meglumine antimonate after intramuscular and subcutaneous administration in dogs. Am J Trop Med Hyg 57(4):403-406