Pharmacy

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Below are listed some of the common drugs used in canine medicine. See the FDA Green book for a comprehensive list of approved veterinary medicines.

Drug

Indications Dose Route Frequency
Acarbose Diabetes mellitus 12.5 - 20 mg Oral with each meal
Acemannan Immunomodulation 1 - 2 mg/kg Intralesional, IP or SQ weekly
Acepromazine Sedation, restraint 0.05 - 2.25 mg/kg SQ, IM, PO q 8 - 12hrs
Aortic thromboembolism 0.15 - 0.3 mg/kg SQ q 8 - 12hrs
Amphetamine and pseudoephedrine toxicosis 0.05 -1.0 mg/kg IV, IM, SQ q 8 - 12hrs
Acetazolamide Glaucoma 5 - 10 mg/kg PO q 8 - 12hrs
Acetylcysteine Mucolytic (Asthma), Acetaminophen toxicity 140 mg/kg IV loading dose
5 - 10 mg/kg PO every 12 hours
Acetylsalicylic acid Antipyretic 6 - 10 mg/kg PO q 48 - 72hrs
Antithrombotic 25 mg/kg PO 2 times/wk
Anti-inflammatory 10 - 20 mg/kg PO q 48 hrs
Analgesia 10 mg/kg PO q 48hrs
Actinomycin D Chemotherapy / antimicrobial 0.5 - 0.9 mg/m2 IV once every 3 weeks
S-Adenosylmethionine Glutathione replenisher - chronic hepatitis, hepatic encephalopathy, portosystemic shunt 20 - 30 mg/kg PO q 24hrs
Aglepristone Mesalliance 10mg/kg SQ stat
Albendazole Lungworm 50 mg/kg PO daily for 21 days
Albuterol sulphate Bronchodilation 90 µg metered dose inhaler q 6 - 8hrs
Alfaxan general anesthesia 1 - 2 mL per 5 kg bodyweight IV bolus or slowly IV
Allopurinol Urate uroliths 10 mg/kg PO q 8 - 12hrs for 30 days
Alprazolam Anxiolytic 0.125 - 0.25 mg/dog PO q 12hrs
Aluminium carbonate gel Phosphate binder 10 - 30 mg/kg PO with meals q 8hrs
Aluminium hydroxide Antacid 20 - 30 ml PO q 2 - 4 hrs
Phosphate binder 30 - 90 mg/kg PO with meals q 8 - 24 hrs
Amantadine Analgesia for chronic pain 3 - 5 mg/kg PO daily for 7 - 14 days
Amikacin Susceptible infections 15 - 22 mg/kg IM, IV, SQ q 24hrs
Aminophylline Asthma 4 - 6.6 mg/kg PO q 8 - 12hrs
2 - 5 mg/kg IV infusion q 12hrs
5-aminosalicylic acid ulcerative colitis 20 mg/kg PO q 24 hrs
Amitriptyline (Endep-10) Analgesia 2 mg/kg PO q 24 hrs
Amlodipine besylate Systemic hypertension 0.625 mg PO q 24 hrs
Ammonium chloride Struvite dissolution 800 mg PO q 24 hrs
Amoxicillin/clavulanate Susceptible infections 10 - 20 mg/kg PO q 12 hrs
Amoxil Susceptible infections 4 - 11 mg/kg PO q 12 hrs
Amphetamine CNS stimulation during certain toxicoses 5 mg PO q 12 hrs
Amphotericin B Systemic mycoses 0.15 - 1 mg/kg in 5% dextrose IV q 48 hrs to a total cumulative dose of 10mg/kg
SQ diluted 1:10 in saline
Ampicillin Susceptible infections 20 - 60 mg/kg PO q 8 - 12 hrs
Amprolium Coccidiosis 60 - 100 mg/kg PO q 24 hrs x 5 d
With sulfadimethoxine 150 mg/kg PO q 24 hrs x 5d
Ascorbic acid Antioxidant 25 - 125 mg/kg/day PO q 24hrs
Acetaminophen toxicosis 30 mg/kg PO, SQ 6 - 7 treatments
Asparaginase Lymphosarcoma 10,000 U/m2 IV weekly as part of a protocol
Aspirin Antipyretic 6 - 10 mg/kg PO q 48 - 72hrs
Atenolol ß1-blocker for Hypertrophic cardiomyopathy + Hypertension 6.25 mg/cat PO q 24hrs
Atipamezole Medetomidine reversal equivolume IM as needed
Atovaquone Toxoplasma spp, Babesia spp, Pneumocystis spp 10 - 15 mg/kg with fatty meal PO q 8 hrs x 21 days
Atracurium Paralytic anaesthetic agent 0.1 - 0.25 mg/kg IV repeated q 30mins
Atropine Pre-anaesthetic medicant, Sinus bradycardia 0.02 - 0.04 mg/kg IM, IV, SQ as required
Organophosphate toxicity 0.2 - 2.0 mg/kg IM, SQ q 2hrs
Aurothioglucose Pemphigus, periodontitis and pododermatitis 1 - 2 mg IM weekly
Azathioprine Enteritis 0.2 -0.3 mg/kg PO q 24 - 48hrs
Immune-mediated haemolytic anaemia 1 mg/kg PO q 24 - 48hrs
Immunosuppression 1.1 mg/kg PO q 48hrs
Azithromycin Susceptible infections 5 mg/kg PO q 24 - 48 hrs
Susceptible infections 80 mg stat PO weekly x 3
Azodyl Probiotic 1 capsule PO q 12 - 24 hrs
Aztreonam Susceptible infections 12 - 25 mg/kg IV, IM q 8 - 12 hrs
Baytril Susceptible infections 5.0 - 20.0 mg/kg PO, SQ, IM, IV (with caution - may cause blindness) q 24hrsfor 7 - 10 days
Beclomethasone Anti-inflammatory 200 mg Inhalant as required
Benazepril Afterload reduction (chronic renal disease, congestive heart failure) 0.25 - 0.5 mg/kg PO q 24hrs
Benzimidazole Trypanosomiasis 5 mg/kg PO q 24hrs for 4 months
Benzocaine Local anaesthetic 1 - 5 ml SQ as required
Benzoyl peroxide Seborrhoea, antibacterial leave on skin for 10mins q 3 - 4 days for 2 weeks
Betamethasone Anti-inflammatory 0.1 - 0.2 mg/kg PO q 12 - 24hrs
Bethanechol Bladder atony, dysautonomia, cystitis 1.25 - 5.0 mg PO q 8- 12 hrs
Bisacodyl Constipation 2 - 5 mg/dog PO q 24hrs as needed
Bleomycin Chemotherapy 10 µg/m2 IV, SQ q 24hrs for 4 days, then weekly; max dose 200mg/m2
Bran Stool softener 1 - 2 teaspoons/400g food PO as needed
Brewer's yeast B vitamin source 0.2 mg</span> PO q 24 hrs
Bromhexine hydrochloride Mucolytic for asthma 2 mg/kg PO q 12 hrs for 7 - 10 days
Bromide Anticonvulsant 30 - 60 mg/kg PO q 12 hrs
Bromocriptine Cushing's syndrome, False pregnancy, lactation cessation 10 - 30 µg/kg PO q 24 hrs for 10 - 16 days
Budesonide Asthma, ulcerative colitis 1 mg/dog PO daily
Bunamidine Cestodes - Taenia spp, Spirometra spp, Diphyllobothrium spp 20 - 50 mg/kg PO after 3 hr fast
Bupivicaine hydrochloride Local Anaesthetic 0.22 - 3.0 ml/cat Epidural stat
Buprenorphine Opioid analgesia 0.005 - 0.01 mg/kg IV, IM q 4 - 8 hrs
Buspirone Behavioural therapy 0.5 - 1.0 mg/kg PO q12-24hrs
Busulfan Chronic myelocytic leukaemia 3 - 4mg/m2 or 0.1 mg/kg PO q 24 hrs
Butorphanol Preanesthetic 0.05 - 0.4mg/kg with ACP IV, IM, SQ
Antiemetic 0.2 - 0.6 mg/kg SQ, IM, IV
Analgesia 0.1 - 0.8 mg/kg PO q 6 - 12 hrs
Cabergoline Induction of estrus/abortion/pyometra 5 μg/kg/day PO, SQ q 24 hrs
Calcitriol Hypoparathyroidism, hyperparathyroidism 1.5 - 3.0 ng/kg PO q 24 hrs
Calcium carbonate Nutritional supplement 1/2 tsp PO daily
Phosphate binder 60 - 100 mg/kg PO daily
Calcium chloride 10% Ventricular asystole 1 ml/9kg or 0.1 - 0.3ml/kg IV (slowly) stat
Hypocalcaemia 1 ml/9kg IV stat
Calcium citrate Calcium replacement, cystitis 10 - 30 mg/kg PO q 8 hrs
Calcium EDTA Lead poisoning 100 mg/kg/day SQ daily for 5 days
Calcium gluconate Ventricular asystole 0.5 - 1.5 ml/kg IV (slowly) as required
Hypocalcemia, hyperkalemia 0.5 - 1.5 ml/kg IV (slowly) as required
Capstar Fleas 1 tab PO daily as needed
Captopril Vasodilator 2 - 3 mg/dog PO q 8 - 12 hrs
3 - 6.25 mg/dog PO q 12 hrs
Carbenicillin cystitis 10 - 55 mg/kg PO q 8hrs
Carboplatin Chemotherapy 200 mg/m2 IV q 4 weeks
Carmustine Chemotherapy 50 mg/m2 IV q 6 weeks
Carprofen Analgesia 1 - 4 mg/kg SQ stat
0.5-1.0 mg/kg PO q 24hrs
Cartrofen Analgesia 1 - 4 mg/kg SQ stat
Cefadroxil Susceptible infections 10 mg/kg PO q 24 hrs for 1 - 4 weeks
Cefovecin Susceptible infections 8 mg/kg (0.5 cc) SQ q 2 weeks x 3
Cephalexin Susceptible infections 10 - 35 mg/kg PO q 8 - 12 hrs

Cerenia

Anti-emetic 1.0 mg/kg SQ/PO q 24 hrs for 4 days, then rest 2 days
Charcoal, activated Adsorbent for poisonings 1 - 8 g/kg PO as needed
Chlorambucil Chemotherapy, ulcerative colitis 0.1 - 0.5 mg/kg PO q 48 - 72 hrs
pemphigus 0.1 - 0.2 mg/kg PO q 48 hrs with prednisolone
Chloramphenicol Susceptible infections 10 mg/kg PO q 12hrs
Chlorhexidine 0.5% Burns dilute 1:40 with saline topically q 24hrs
Chlorothiazide Diuretic 10 - 40 mg/kg PO q 12 hrs
Partial ADH deficiency 20 - 40 mg/kg PO q 12 hrs
Chlorpheniramine Antihistamine 1 - 2 mg/dog PO q 8 - 12 hrs
Chlorpromazine vomiting, pancreatitis 0.2 - 0.5 mg/kg IM or SQ q 6-8hrs
Cholecalciferol (Vit D) hyperparathyroidism, hypocalcaemia 500 - 2000 U/kg PO q 24 hrs
Chondroitin Arthritis 50 - 100 mg/dog PO q 24 hrs
Cimetidine Oesophagitis, antiemetic, gastritis 5 - 15 mg/kg PO, IV, IM q 8 - 12 hrs
Ciprofloxacin Susceptible infections 11 - 15 mg/kg PO q 24 hrs
Cisapride (Prepulsid) constipation, megacolon 0.5 - 5.0mg/cat PO q 12 hrs
Cisplatin Chemotherapy 100 mg/m2 IV q 4 weeks x 2
Clarithromycin Mycobacterium spp 50 mg/dog PO q 12 hrs
Clavulox Susceptible infections 10 - 20 mg/kg PO q 12 hrs
Clindamycin Anaerobic infections 5 - 11 mg/kg PO q 12 hrs
Stomatitis, Pancreatitis 22 mg/kg PO q 24 hrs
Exocrine pancreatic insufficiency 5 - 10 mg/kg PO q 6 - 8 hrs
Enteroepithelial cycle 12.5 - 50 mg/kg PO q 12 hrs
Clofazimine Mycobacterium spp 4 - 8 mg/kg PO q 24 hrs for 6 weeks
50 mg/cat PO q 48 hrs
Clomipramine obsessive compulsive disorders, aggression 0.5 - 2.0 mg/kg PO q 12 - 24 hrs
Clonazepam Seizures, obsessive compulsive disorders, separation anxiety 0.5 mg/kg PO q 8 - 12 hrs
Clopidogrel thromboembolism, hypertrophic cardiomyopathy 18.75 - 75 mg PO q 24 hrs
Clorazepate separation anxiety 1 - 2 mg/kg PO q 8 - 12 hrs
Clotrimazole Fungal infections apply to lesion topical q 12 hrs
Fungal infections 60 ml of 1 g/dL of polyethylene glycol intranasal over 1 hr under general anaesthesia
Cloxacillin Susceptible infections 20 - 40 mg/kg PO, IM, IV q 4 - 8 hrs
Coal tar shampoos Seborrhoea Keep in contact with skin for 10 mins Topically q 24 hrs
Cobalamin see Vit B12
Cod liver oil 1 teaspoon / 10 kg
Codeine Pain relief 0.5 - 4 mg/kg PO q 6 - 12 hrs
Antitussive, analgesia 0.1 - 0.3 mg/kg PO q 4 - 6 hrs
Colchicine Antifibrotic 0.01 - 0.3 mg/kg PO q 4 - 6 hrs
Colony stimulating factor cyclic neutropenia 2.5 - 5.0 mg/kg (3 × 107 IU/kg) SQ q 24 hrs
Convenia Susceptible infections 8 mg/kg (0.5 cc) SQ q 2 weeks x 3
Corticotrophin gel (ACTH) Response test pre-ACTH sample 0.5 - 2.2 IU/kg IM
Cortisone acetate hypoadrenocorticism 1 mg/kg PO, IM q 24 hrs
Cosyntropin pre-ACTH sample 0.125 mg/dog IV
Cyanocobalamin Vit B12 deficiency 50 - 1000 µg</span> PO, IM, SQ q 24 hrs
Cyclizine Antiemetic 4 mg/kg IM q 8 hrs
Cyclophosphamide Chemotherapy 100 mg/m2 PO q 3 weeks with doxorubicin
Cyclosporin thrombocytopenia, pemphigus, sebaceous adenitis 4 - 6 mg/kg 4hr IV infusion q 24 hrs (avoid extravasation)
3 - 7 mg/kg PO q 12 hrs
Cyclosporin ophthalmic keratoconjunctivitis sicca 1 - 2% solution drop in eye q 12 hrs
Cyclothiazide diuretic 0.5 - 1.0 mg/kg PO q 24 hrs
Cytarabine Chemotherapy 30-50 mg/kg IV, IM, SQ once a week
100 mg/m2 IV. IM, SQ q 24 hrs for 4 days then
20 mg/m2 Intrathecal q 24 hrs for 1 - 5 days
Dacarbazine Lymphoreticular neoplasms 200 - 250 mg/m2 IV q 24 hrs for 5 days, every 21 days
Soft tissue sarcomas 1000 mg/m2 IV infusion over 6 - 8hrs, every 21 days
Dactinomycin Chemotherapy 0.015 mg/kg IV q 24 hrs for 3 - 5 days, wait 3 weeks then
0.1 - 1.5 mg/m2 IV weekly
Dalteparin DIC, Thrombosis 70 IU/kg SQ q 24 hrs
Dapsone Mycobacterium spp 1.1 mg/kg PO q 12 hrs for 4 - 6 weeks
Deferoxamine mesylate Iron chelator 10 mg/kg IV, IM, SQ q 2 hrs for 2 doses then q 8 hrs for 24 hrs
Reperfusion (ischaemia) injuries 50 mg/kg IV over 5 mins
Deprenyl hyperadrenocorticism 1 - 2 mg/kg PO q 24 hrs
Desmopressin acetate diabetes insipidus 0.3 µg/kg IM q 12 - 24 hrs
Desoxycorticosterone acetate hypoadrenocorticism 0.2-0.4 mg/kg conjunctivally q 24hrs, max 5mg
Desoxycorticosterone pivalate hypoadrenocorticism 25 mg IM stat
Dexamethasone central oedema, spinal cord trauma, DJD, other CNS trauma 2 mg/kg IV then,
1 mg/kg IV, SQ q 8 - 12 hrs, then
0.1 mg/kg IV, SQ, PO q 8-12hrs
hydrocephalus 0.25 mg/kg IV, IM, PO q 6 - 8 hrs
shock, anaphylaxis 4 - 6 mg/kg IV (slowly)
immune-mediated disease 0.25 - 1.25 mg/kg PO q 12 - 24 hrs
0.1 - 0.15 mg/kg SQ, PO q 12 hrs for 5 - 7 days, then taper dose
hypoadrenocorticism 0.1 - 0.5 mg/kg SQ, IV with mineralocorticoids
asthma 1 mg/kg IV then
0.25 - 1.0 mg/cat PO q 8 - 24hrs
Dexrazoxane iron chelation for doxorubicin-induced cardiotoxicity 25 mg/kg (ratio of 10-20:1 dexrazoxane : doxorubicin) IV 15 mins before doxorubicin
Dextran 40 Shock 10 - 20 ml/kg IV q 24 hrs
Dextran 70 Volume expander 10 - 20 ml/kg IV q 24 hrs to effect
Dextromethorphan coughing 0.5 - 2.0 mg/kg PO, SQ, IV q 6 - 8 hrs
Dextrose, 50% hypoglycemia, insulin overdose 2 ml/kg PO
0.25 - 1.0 ml/kg IV
Dextrose, 5% hypoglycemia, insulin overdose 40 - 50 ml/kg IV, SQ, IP as needed
Diazepam Pre-med, Behavior modification 0.5 - 2.2 mg/kg PO as needed
seizures 0.15 - 0.70 mg/kg PO, IV q 8 hrs
status epilepticus, toxins 0.5 - 1.0 mg/kg IV in increments of 5 - 20 mg
strychnine-induced seizures 2 - 5 mg/kg IV as needed
0.5 mg/kg IV
Dichlorphenamide Glaucoma 3 - 5 mg/kg PO q 8- 12 hrs
Dicloxacillin Susceptible infections 10 - 50 mg/kg PO q 6 - 8 hrs
Diethylcarbamazine heartworm disease 6.6 mg/kg PO q 24 hrs
Diethylstilboestrol incontinence 0.01-0.02 mg/kg PO q 24 hrs
Difloxacin Susceptible infections 5 - 10 mg/kg PO q 24 hrs
Digoxin Congestive heart failure 0.005 - 0.008 mg/kg PO q 12 hrs
Dihydrotachysterol milk fever, hypoparathyroidism 0.03 - 0.06 mg/kg PO q 24 hrs for 3, then
0.01-0.02 mg/kg PO q 24hrs
Diltiazem hypertension, hypertrophic cardiomyopathy, supraventricular tachycardia 0.5 - 2.5 mg/kg PO q 8 hrs
Dimenhydrinate Antihistamine 1.0 - 3.0 mg/kg PO, IM, IV as needed
Dimercaprol Arsenic toxicosis 2.5 -5.0 mg/kg IM q 4 hrs for 2 days, then q 8hrs for 3 days, then q 12hrs for 10 days
Dimethylsulfoxide Spinal cord trauma, amyloidosis 0.5 - 1 g/kg IV (10%) q 6 - 8 hrs over 45 min
Diminazine aceturate Babesia spp, Trypanosoma spp 2.0 - 3.5 mg/kg IM Once
3.5 mg/kg IM, SQ q 24 hrs for 2 days
Dinoprost see prostaglandin F2a
Diphenhydramine Antihistamine 2 - 4 mg/kg PO q 6 - 8 hrs
mast cell tumour, antiemetic 2 mg/kg IM, IV q 12 hrs as needed
Diphenoxylate ulcerative colitis 0.05 - 0.1 mg/kg PO q 12 hrs
Diphenylthiocarbazone Thallium toxicosis 50 - 70 mg/kg PO q 8 hrs
Diphemanil methylsulphate bronchodilator 1.8 mg/kg IM q 12 hrs
Dipyridamole thromboembolism 4 - 10 mg/kg PO q 24 hrs
Disodium EDTA Calcium keratopathy 0.37% solution topically lavage cornea for 15 - 20 mins
Dobutamine Positive ionotrope 0.5 - 2.0 µg/kg/min IV infusion (caution) 1 min
Dolasetron antiemetic 0.6 mg/kg PO, IV, SQ q 24 hrs
Dopamine hypotension, shock, inotropic agent 2 - 25 µg/kg IV infusion 1 min
Doxapram Respiratory stimulant in neonates 1 - 5 mg/kg IV (umbilical vein) as needed
1 - 2 drops PO as needed
Doxorubicin chemotherapy 10 - 30 mg/m2 IV q 21 days
Doxycycline Susceptible infections 5 - 10 mg/kg PO, IV q 12 - 24 hrs
Edrophonium myasthenia gravis diagnosis 2.5 mg/dog IV stat
Emodepside anthelmintic 1 x vial topically monthly
Enalapril hypertension, congestive heart failure, valvular endocardiosis 0.25 - 0.5 mg/kg PO q 12 - 24 hrs
Enilconazole 10% Aspergillus spp 5% solution (1:1 in water) topically q 12 hrs for 7 - 10 days
10-20 mg/kg (10% solution: 50:50 in water instil into nasal sinus q 12hrs for 10 - 14 days
Enrofloxacin Susceptible infections 5.0 - 20.0 mg/kg PO, SQ, IM, IV (with caution - may cause blindness) q 24 hrs for 7 - 10 days
Ephedrine bronchodilator, incontinence 2.0 - 5.0 mg/kg PO q 8 - 12 hrs
Epinephrine cardiac arrest 0.2 ml/kg IV, intratracheal q 5 - 15 min as needed
Epsiprantel Dipylidium spp, Taenia spp 2.5 - 2.75 mg/kg PO stat
Ergocalciferol Vitamin D 500 - 2000 IU/kg PO q 24 hrs
Erythromycin Susceptible infections 10 - 22 mg/kg PO, IV q 8 hrs
Erythropoietin anemia 50 - 100 IU/kg SQ 3 x weekly for 12 weeks then twice weekly (as need to maintain PCV at 35%)
400 IU/kg IV, SQ once a week
Esmolol Selective B1 blockade 0.05 mg/kg slow IV loading dose, then
50 - 200 µg/kg IV infusion per min
Estradiol cypionate mesalliance 125 - 250 µg IM between 40hrs and 5 days post-coitus
Ethosuximide seizures 40 mg/kg PO load, then
20 mg/kg PO
EDTA anticoagulant, chelation 1 mg/kg IV q 2hrs
Etidronate disodium hypercalcaemia 10 mg/kg PO q 2 hrs
Etomidate general anesthesia 0.5 - 3.0 mg/kg IV as needed
With opioids 0.5-1.0 mg/kg IV as needed
Etretinate dermatopathy 1 - 2 mg/kg PO q 24 hrs
Famotidine antacid 0.5 mg/kg IM, SQ, PO q 12 - 24 hrs
Febantel anthelmintic 10 mg/kg per 1mg/kg praziquantel PO q 24 hrs for 3 days
Fenbendazole anthelmintic 25 - 50 mg/kg PO q 12 hrs for 3-14 days
Fentanyl analgesia 0.01 mg/kg IV, SQ, IM
Fitergol cognitive dysfunction syndrome 1 - 5 mg/dog PO q 24hrs
Flavoxate Incontinence (Detrusor hyperspasticity) 100 - 200 mg/dog PO q 6 - 8 hrs
Florfenicol Susceptible infections 22 - 50 mg/kg PO, IM, SC q 12 hrs
Fluconazole fungal infections 2.5 - 10.0 mg/kg PO with food q 12 - 24 hrs
Flucytosine Cryptococcus spp 30 - 50 mg/kg PO q 6 - 8 hrs
Fludrocortisone hypoadrenocorticism 0.1 - 0.2 mg/dog PO q 24 hrs
Flumazenil hepatic encephalopathy 0.2 mg/dog IV as needed
Flumethasone anti-inflammatory 0.15 - 0.3 mg/kg IV, IM, SQ q 24 hrs
Flunixin meglamine analgesic, anti-pyretic 0.5 - 2.2 mg/kg IV, IM, SQ oid for 3 days, then repeat after 4 days
Fluoxetine Behavioural problems 0.1 - 2.0 mg/kg PO q 24 hrs
Flurazepam seizures 0.2 - 0.4 mg/kg PO q 4 - 7 days
Flurbiprofen Conjunctivitis 0.2 - 0.4 mg/kg Topically q 8 - 12 hrs
Folic acid Dietary supplement 0.5 - 1.0 mg/kg PO q 24 hrs
Follicle stimulating hormone (FSH) Induction of oestrus 500 IU HCG IV, IM, SQ q 24 hrs for 5 days
Fomepizole Ethylene glycol toxicity 20 mg/kg IV stat
Furosemide diuretic 2 - 4 mg/kg IV, IM, PO q 8 - 12 hrs as needed
Gabapentin Epilepsy 10 mg/kg PO q 8 - 12 hrs
Gamma globulin Immune-mediated disease 1 g/cat IV q 6 - 12 hrs
Gentamicin Susceptible infections 6 - 8 mg/kg IM, SQ, IV q 24 hrs
Glimipiride Non-insulin-dependant diabetes mellitus 0.25 - 0.5 mg/kg PO q 24 hrs
Glipizide Non-insulin-dependant diabetes mellitus 0.25 - 0.5 mg/kg PO q 8 - 12 hrs
Glycopyrrolate Bundle branch block 0.005 - 0.010 mg/kg IV, IM as needed
Gold sodium thiomalate Immune-mediated disease 0.25 - 1.0 mg/kg IM weekly x 3; 2nd + 3rd week at 2 - 10 mg/cat
Gonadotropin releasing hormone (GnRH) Ovarian cystadenoma, detection of ovarian remnant syndrome 25 µg/dog IM single treatment
Granisetron Chemotherapy-associated vomiting 0.1 - 0.5 mg/kg IV, PO q 12 - 24 hrs
Granulocyte colony stimulating factor Neutropenia 3 - 10 µg/kg SQ q 12 - 24 hrs
Griseofulvin Antifungal 10 - 30 mg/kg PO q 24 hrs for 4 weeks
Guaifenesin Tranquiliser 44 - 88 mg/kg IV stat
Halofuginone Coccidiostat, Immunosuppressant 100 µg/kg PO q 24 hrs
Halothane General anesthesia Induction: 3% Inhalant stat
Maintenance: 0.5-1.5% Inhalant as needed
Haemoglobin (polymerised bovine) Blood replacement 10-30 ml/kg IV stat
Heparin Thromboembolism, thrombophlebitis Initial dose: 100-200 IU/kg IV then
Maintenance dose: 50-100 IU/kg SQ q 6 - 8hrs
Thromboembolism Induction 1000 IU/kg IV then
Maintenance: 50 IU/kg SQ q 8hrs
Pancreatitis 50-1000 IU/kg SQ q 8 - 12hrs
DIC 75-100 IU/kg IV, SQ q 6hrs
Lipoprotein lipase provocation test 100 IU/kg IV test lipids before and 15 mins after heparin
Heparin, LMW see Dalteparin
Hetacillin Susceptible infections 10 - 20 mg/kg PO q 8 - 12 hrs not associated with feeding
Hetastarch (Hydroxyethyl starch) Plasma volume expander 10 - 20 ml/kg IV as needed
Human gammaglobulin Immune-mediated disease 0.5 - 1.5 g/kg IV q 12 hrs (infusion)
Hydrocodone Antitussive 0.22 mg/kg PO q 12 hrs
Hyaluronate sodium Synovitis 0.5 - 1.0 mg/kg intra-articular q 7 days
Hydralazine Vasodilator: congestive heart failure 0.5 mg/kg, titrate up to 0.5 - 0.8 mg/kg PO q 12 hrs
Hydrochlorothiazide Hypertension 0.5 - 2.0 mg/kg PO q 12 - 24 hrs
Nephrogenic diabetes insipidus 0.5 - 5.0 mg/kg PO q 12 hrs
Hypoglycaemia 2 - 4 mg/kg PO q 12 hrs
Calcium oxalate uroliths 2 mg/kg PO q 12 hrs
Hydrocortisone Replacement therapy 0.5 - 1.0 mg/kg PO q 24 hrs
Anti-inflammatory 2.5 - 5.0 mg/kg PO q 12 hrs
Hydrocortisone aurate Hypoadrenocorticism 0.1 - 0.2 mg/kg IM q 8 - 12 hrs
Immune-mediated haemolytic anaemia 2 - 4 mg/kg IM q 12 - 24 hrs
Hydrocortisone sodium succinate Shock 8 - 150 mg/kg IV stat
Hydrogen peroxide (3%) Emetic 5-10 ml/cat PO stat
Hydromorphone Analgesia 0.05 - 0.1 mg/kg IM, SQ every 24 hrs
Hydroxyurea Primary polycythemia 25 - 30 mg/kg PO q 3 days
Chronic granulocytic leukaemia 0.5 g/m2 PO q 12hrs for 4-6 weeks, then halve dosage
Hydroxyzine Antihistamine 5-10 mg/cat PO q 12hrs
Hypertonic saline Shock 2-6 ml/kg rapid IV infusion stat
Idarubicin HCl Antiviral 2.0 mg/kg PO q 24hrs for 2 days, then repeat q21 days
Idoxuridine Ocular herpes viral infection 0.1% solution: 1 drop topically q 4 - 6 hrs
0.5% ointment topically q 1 hr
Imatinib mesylate Chemotherapy 10 mg/kg orally once daily
Imidacloprid Fleas 100 mg/ml topically 0.1 cc/kg monthly
Imidocarb Ehrlichia spp 5 mg/kg IM every 14 days x 2
Imidapril Congestive heart failure and Chronic renal disease 0.5 mg/kg PO q 24hrs
Imipenem-cilastin Susceptible infections 2 - 10 mg/kg IM or slow IV q 6 - 8 hrs
Imipramine Behavioural modification, urinary incontinence 2.5 - 5.0 mg/cat PO q 12 hrs
Insulin, glargine Diabetes mellitus 0.25-5.0 U/kg SQ q 12hrs, adjust as needed
Insulin, lente Diabetes mellitus 0.5 U/kg SQ q 12 - 24hrs
Insulin, NHP Diabetes mellitus 1 - 3 U/dog SQ q 12 - 24hrs
Insulin, PZI Diabetes mellitus 1 - 3 U/dog SQ q 12 - 24 hrs
Insulin, regular Diabetes mellitus 1 - 2 U/dog SQ q 6 - 8 hrs
Insulin, ultralente Diabetes mellitus 1-3 U/dog SQ q 12 - 24hrs
Interferon a2, human recombinant Immunostimulant 15 - 30 U/dog IM, SQ, PO q 24 hrs on alternate weeks
Iodine Hyperthyroidism 50 - 100 mg/dog PO q 24 hrs
Iodide sodium, potassium 20% solution Hyperthyroidism 20 mg/kg PO q 12 - 24 hrs
Iopamidol Myelography 0.25 ml/kg intrathecal stat
Ipecac syrup Emetic 2 - 6 ml/dog PO stat
Ipodate Hyperthyroidism (short term) 15 mg/kg PO q 12hrs
Iron dextran anemia 50 mg IM at 18 days of age
Isoflurane Gaseous anaesthesia

Induction: 5%

Maintenance: 1.5-2.5%

Inhalation stat
Isoniazid Mycobacterium spp 10 - 20 mg/kg PO q 24 hrs
Isopropamide Bundle branch block 0.2 - 0.4 mg/kg PO q 8 - 12 hrs
Antidiarrhoeal, GIT hypermotility 0.2 - 1.0 mg/kg PO q 12 hrs
Isoproterenol Bundle branch block 0.04 - 0.08 µg/kg IV infusion as needed
Isosorbide dinitrate Vasodilator, osmotic diuretic, megaoesophagus 2.5 - 5.0mg PO q 12 hrs
Itraconazole fungal infections 5 - 10 mg/kg PO q 12 - 24 hrs
Ivermectin Heartworm disease prophylaxis 24 µg/kg PO once monthly
Kanamycin Susceptible infections 10 - 15 mg/kg IV, IM, SQ q 12 hrs
GI tract bacterial overgrowth 10 - 12 mg/kg PO q 8 - 12 hrs
Kaolin / pectin GI tract protectant 1 - 2 ml/kg PO q 2 - 6 hrs
Ketamine general anesthesia 7 - 11 mg/kg IV, IM stat
Ketoconazole fungal infections 5.0 - 10.0 mg/kg PO q 12 - 24 hrs
Ketoprofen analgesic 0.2 - 1.0 mg/kg PO, IM, SQ q 24 hrs for less than 5 days
L-asparaginase chemotherapy 10,000 U/m2 IV weekly as part of a protocol
Lactated Ringer's solution Rehydration 40 - 50 ml/kg IV q 24 hrs
Lactilol Stool softener, hepatic encephalopathy 250 ml PO q 12 hrs
Lactoferrin periodontitis 40 mg/kg Topical q 24 hrs
Lactulose megacolon, hepatic encephalopathy 2.5-5.0 ml PO q 8 - 12 hrs
Lamasil fungal infections 20 - 30 mg/kg PO q 24 hrs for 4 - 10 weeks
Leucovorin Methotrexate toxicity 3 mg/m2 IM within 3 hrs of poisoning
Levallorphan Opioid toxicity/overdose 0.02 - 0.20 mg/kg IV as needed
Levamisole heartworm disease 10 mg/kg PO q 24 hrs for 7 days
Levetiracetam seizures, cognitive disorder 15 - 20 mg/kg PO q 8 - 12 hrs
Levodopa hepatic encephalopathy 6.8 mg/kg initially, then 1.4mg/kg PO q 6 hrs
Thyroxine Hypothyroidism 10-30 µg/kg PO q 12hrs
Lidocaine Ventricular arrhythmias, epidural 0.25 - 1.0 mg/kg IV, intrathecal stat
Lime sulphur Sarcoptes spp 1:40 dilution Topically weekly for 6 weeks
Lime water Alkaline gastric lavage 5 ml/kg PO stat
Lincomycin Susceptible infections 11 - 33 mg/kg PO, IV, IM q 12 - 24 hrs
Lisinopril congestive heart failure, hypertension 0.25 - 5.0 mg/kg PO q 24 hrs
Lobaplatin chemotherapy 35 mg/m2 IV q 3 hrs
Lomustine chemotherapy 100-150 mg/m2 PO q 6 weeks (subsequent dose based on WBC)
Loperimide Antidiarrhoeal 0.1 - 0.3 mg/kg PO q 12 - 24 hrs
Luteinizing hormone Stimulate ovulation 50 IU IM after mating
Magnesium sulphate (25%) Hypomagnesemia 5 - 15 mmol IM, IV over 1 - 2 hrs
Mannitol 5-20% oliguric renal failure 0.25 - 1.0 g/kg IV over 15 - 60 min q 4 - 6 hrs to maintain urine flow
Glaucoma 1 - 3 mg/kg IV over 15 - 20 min
CNS oedema 1.5 mg/kg IV stat
Marbofloxacin Susceptible infections 2.75 - 5.5 mg/kg PO q 24 hrs
Maropitant Anti-emetic 1.0 mg/kg SQ/PO q 24 hrs for 4 days, then rest 2 days
Mebendazole Parasites 22 mg/kg PO q 24 hrs for 3 days
Meclizine antiemetic 12.5 mg PO q 24 hrs, 1 hr before driving
Medetomidine analgesia, sedative 50-150 µg/kg IV, IM stat
Medroxyprogesterone acetate aggression 1 - 2 mg/kg IM once weekly, stop 7-10 days before parturition
Megestrol acetate estrus suppression 0.5 - 1.0 mg/kg PO q 24 hrs for 10 days, then q 48hrs for 5 treatments, then as needed
Meglumine antimonate Leishmaniasis 5 - 30 ml/dog IV, IM, IP q 48 - 72 hrs
Melatonin Anterior uveitis 0.01 - 1.0 mg PO q 24hrs
Meloxicam analgesia 0.01 - 0.03 mg/kg PO q 24 hrs as needed
Melphalan chemotherapy 0.05 mg/kg PO q 24 hrs for 2 weeks, then q 48hrs
Mepivacaine Local analgesia 1 - 5 ml of 2% solution SQ as needed
Mesna Haemorrhagic cystitis associated with cyclophosphamide 40% of cyclophosphamide dose PO, IV, IM, SQ q 3 hrs x 6 at time of cyclophosphamide treatment, follow with repeat dose (24 hr infusion)
Metamucil Laxative 2-4 g in moistened food q 12 - 24 hrs
Metaproterenol Bronchodilation 0.325 - 0.65 mg/kg PO q 4 - 6 hrs
Metaraminol Vascular support during shock 0.01 - 0.1 mg/kg IV slowly stat
Metformin diabetes mellitus) 2 mg/kg PO q 12 hrs
Methazolamide glaucoma 1 - 2 mg/kg PO q 12 hrs
Methicillin Susceptible infections 20 mg/kg IM, IV q 6 hrs
Methocarbamol Muscle relaxation 20 - 66 mg/kg PO q 8 - 12 hrs
Methohexital Anaesthesia induction 2.5% solution: 11 mg/kg IV stat
Methotrexate sodium Chemotherapy 2.5 mg/m2 PO q 24hrs or 2 - 3 x weekly, in a protocol on day 14 with 5 mg prednisolone PO q 12hrs
Carcinomas, sarcomas 10-15 mg/m2 PO q 1 - 3 weeks
Methoxamine (a1-agonist) Vasopressor: cardiac arrest, shock 200-250 µg/kg or 40-80 µg/kg IM stat
Methoxyflurane Inhalation anaesthesia Induction: 3%, Maintenance: 0.5-1.5% Inhalation stat
Methscopolamine bromide Anti-emetic 0.3-1.0 mg/kg PO q 8hrs (use cautiously)
Methylcellulose Laxative 1.0-1.5 g/cat PO as needed
Methylene blue 0.1% Indicator dye 3 mg / 250 ml 0.9% NaCl IV over 30-40 min
Antidote 1-1.5 mg/kg IV stat
Methylprednisolone Antiinflammatory 0.5-1.0 mg/kg PO q 12hrs
Methylprednisolone acetate Asthma 1-2 mg/kg IM q 7 days
Others 5.5 mg/kg SQ, IM 1 - 24 weeks
Methyltestosterone Anabolic steroid 1 - 2 mg/kg PO q 24 hrs
Testosterone-responsive dermatoses 1-2.5 mg/cat PO q 48hrs
Metoclopramide Gastric motility disorders, antiemetic 0.2 -0.5 mg/kg PO, IM, SQ q 8 hrs
1.0 - 2.0 mg/kg IV q 24 hrs
Gastric reflux 0.2-0.4 mg/kg PO q 8hrs, 30 mins before meals
Metoprolol Atrial fibrillation, hypertrophic cardiomyopathy 0.05 - 3.0 mg/kg PO q 8 hrs
Metronidazole Colitis, Coccidiosis, anaerobic infections 10 - 25 mg/kg PO q 24 hrs for 7 - 14 days
Gingivitis 50 mg/kg PO q 24 hrs
Metyrapone Cushing's syndrome 65 mg/kg PO q 12 hrs
Mirtazepine Antiemetic 0.75 mg/kg PO q 3 days
Misoprostol Mucosal protectant 3 - 5 µg/kg</span> PO q 12 hrs as required
Miconazole cream Fungal infections 1 - 3 cm topically q 24 hrs for 2 - 4 weeks
Midazolam Preanaesthetic, sedation, 0.06 - 0.22 mg/kg IM, IV stat
Control of seizures 0.2-0.5 mg/kg IV stat
Milbemax Heartworm and intestinal worm prophylaxis 0.5 - 2.0 mg/kg PO monthly
Silymarin Free radical scavenger 50 - 250 mg/kg PO q 12 hrs
Mineral oil Laxative 5-10 ml/cat PO, per rectum q 12hrs
Mithramycin Hypercalcaemia, testicular cancer, malignancies 0.25 - 0.50 µg/kg IV q 24 hrs x 2
Mitotane (o,p-DDD) Pituitary-dependant hyperadrenocorticism 25 mg/kg PO q 7 days (maintenance)
Mitoxantrone Anticancer chemotherapy 6.0 - 6.5 mg/m2 IV q 3 - 4 weeks x 4 - 6
Morphine Antitussive, analgesia 0.05 - 0.1 mg/kg SQ, IM q 4 - 6 hrs
Moxifloxacin Mycobacterium spp, Bartonella spp]] 5.0 mg/kg PO q 24 hours
Naloxone stereotypic behaviour 20 mg SQ
Shock 2 mg/kg IV q 1 hr
Opioid antagonist 0.01 - 0.04 mg/kg IV to effect, repeat as needed
Nandrolone Anaemia 2.0 - 10 mg/kg IM weekly
N-acetylcysteine see Acetylcysteine
Neomycin Susceptible infections 7 mg/kg IM, IV, SC q 24 hrs (nephrotoxic)
Hepatic encephalopathy 10 - 20 mg/kg per rectum q 6 hrs
Neostigmine Diagnostic aid for myasthenia gravis 20 µg/kg with 0.04 mg/kg of atropine IV stat
2 mg/kg/day PO q 24hrs, divided doses
Niacin Hypertriglyceridemia 50 - 100 mg/day PO q 24 hrs
Nitenpyram Fleas 1 tab PO daily as needed
Nitroglycerin 2% ointment Vasodilator for pre-load reduction 1/8 - 1/4 inch (0.3-0.6cm) cutaneously q 6 - 8 hrs
Nitroprusside Acute Congestive heart failure 0.5-10 µg/kg IV q 1 min
Norepinephrine Positive ionotrope 0.05 - 0.3 µg/kg IV q 1 min
Novobiocin Susceptible infections 10 mg/kg PO q 8 hrs
Nystatin Susceptible infections 100,000 IU PO q 8 hrs
Octreotide Chylothorax, Acromegaly 0.1 mg SQ q 8 hrs
Ofloxacin Susceptible infections 2.5-10.0 mg/kg PO q 12hrs
Omeprazole Gastritis, gastric ulceration 1 mg/kg PO q 24 hrs
Ondansetron Antiemetic 0.5 - 1.0 mg/kg PO q 24 hrs
Orbifloxacin Susceptible infections 2.5 - 7.5 mg/kg PO q 24 hrs
Ovarid (see Megestrol acetate)
Oxymorphone Preanaesthetic 0.1 - 0.2 mg/kg IM, IV with ACP or atropine
Oxytocin Dystocia 0.5 - 1.0 IU/kg IV, IM, SQ q 2 hrs for max of 3 doses
Paclitaxel Chemotherapy 5 mg/kg IV pre-treat for anaphylaxis
Pancuronium bromide Paralytic agent for controlled anaesthesia 0.044 - 0.11 mg/kg IV stat
Parvaquone Toxoplasmosis 10 - 30 mg/kg IM q 24 hrs
D-penicillamine chronic hepatitis 10 - 15 mg/kg PO q 12 hrs
Penicillin G Susceptible infections 20-30 mg/kg PO q 6 - 8hrs
Pentazocine Analgesia 2.2 - 3.3 mg/kg IV, IM, SQ q 4 hrs
Pentobarbital general anesthesia 25 - 30 mg/kg IV to effect
Status epilepticus 5 - 15 mg/kg IV to effect
Sedation 2 - 4 mg/kg PO q 6 hrs
Pentosan polysulfate Disease modifying agent, arthritis 3 mg/kg IM, SQ q 7 days
Pentoxifylline Dermatomyositis 20 mg/kg PO q 8 - 12 hrs
Autoimmune skin diseases 10 - 15 mg/kg PO q 24hrs
Phenamidine isethionate Babesia spp 7.5 mg/kg IM, SQ q 24hrs x 2
Phenobarbital Status epilepticus 2.5 - 5 mg/kg PO, IM, IV q 12 hrs
Phenoxybenzamine Hypertension, pheochromocytoma 0.5 mg/kg PO q 12 hrs
Detrusor areflexia 0.5 - 2.0 mg/cat PO q 8 - 12 hrs
Relaxation of urinary sphincter 0.5 mg/kg IV stat
Endotoxemia 2.5-10.0 mg/cat PO q 24hrs
Phentolamine hypertension from pheochromocytoma 0.02 - 0.1 mg/kg IV stat
Phenylephrine Vasopressor, decongestant, mydriatic 0.15 mg/kg IV as needed
Phenylpropanolamine incontinence 1.5 - 2.0 mg/kg PO q 8 hrs
Phenytoin Seizures, ventricular arrhythmias 2 - 3 mg/kg PO q 24 hrs
Phosphate (K or Na) Hypophosphatemia 4.5 mg/dl serum phosphate IV over 6 hrs
Physostigmine (Syrup) Myasthenia gravis, Glaucoma, magic-mushroom intoxication 0.25-5.0 mg/cat IM q 12hrs
Phytomenadione See Vitamin K1
Pilocarpine 1% ophthalmic glaucoma 1 drop topically q 6 hrs
Pimaricin Ocular fungal infections 1 drop topically q 3 - 8 hrs
Piroxicam Analgesia, neoplasia 0.3 mg/kg PO q 24 - 72 hrs
Plicamycin Hypercalcemia, testicular cancer, malignancies 0.25 - 0.50 µg/kg IV q 24 hrs x 2
Polyethylene glycol Lubricant, intestinal cathartic 25 ml/kg PO then repeat in 2-4 hrs before GI exam
Polyethylene glycol electrolyte solution Electrolyte replacement 25 ml/kg PO q 2 - 4 hrs
Polymixin B Sepsis 1 - 2 mg/kg IV stat
Posaconazole Aspergillosis 2.5 - 3.75 mg/kg PO q 12 hrs
Potassium chloride Potassium supplementation 0.10-0.25 ml/kg PO q 8hrs
Hypokalemia 0.5 mEq/kg IV not to exceed 0.5 mEq/kg/hr
1 - 3 mEq PO. IV q 24 hrs
10-40 mEq/500 ml of fluid, depending on serum potassium IV, SQ stat
Potassium citrate Urolithiasis 50-75 mg/kg PO q 12hrs
Potassium gluconate Hypokalemia 5-8 mEq/dog PO q 12 - 24 hrs
Potassium iodide fungal infections 6 - 20 mg/kg PO q 24 hrs for 10-14 days
Potassium permanganate (1:2000) Strychnine toxicosis 5 ml/kg in gastric lavage PO stat
Potassium phosphate see Phosphate
Povidone-iodine Burns Apply light coating Topically q 12 - 24 hrs
Pradofloxacin Broad-spectrum antimicrobial 5 - 10 mg/kg PO, SQ q 24 hrs for 7 days
Pralidoxime chloride Organophosphate toxicosis 20 mg/kg IV, IM, SQ q 12 hrs
Praziquantel Dipylidium spp 5 mg/kg PO stat
Paragonimus spp 25 - 30 mg/kg PO q 24 hrs for 5-10 days
Prazosin After load reductions 0.5 - 2.0 mg/dog PO q 8 - 12hrs
Cystitis 0.07 mg/kg PO q 8 - 12 hrs
Prednisolone anti-inflammatory 1 - 2 mg/kg PO q 24 hrs (each evening)
Hypoadrenocorticism 1 mg/kg PO q 12 hrs
Prednisolone acetate Hypoadrenocorticism 0.1-0.2 mg/kg IM q 12hrs
Prednisolone sodium phosphate Shock 15 mg/kg IV q 4 - 6hrs
Prednisolone sodium succinate Allergic bronchitis, asthma 15-30 mg/kg IV, IM to effective dose
Shock 15-30 mg/kg IV q 4 - 6hrs
CNS trauma 15-30 mg/kg IV then taper to effective dose
Pregabalin Epilepsy 5 -10 mg/kg PO q 12 hrs
Prilium Congestive heart failure and Chronic renal disease 150 mg syrup PO 0.5ml q 24hrs
Procainamide Ventricular arrhythmias 62.5 mg/dog PO q 6hrs
Prochlorperazine Antiemetic 0.1 mg/kg IM q 6 hrs
Promazine hydrochloride Pre-anaesthetic 2.2 - 6.6 mg/kg IV stat
Antiemetic 1-2 mg/kg IM, IV q 4 - 6hrs
Promethazine HCl Antihistamine, antiemetic 0.2 - 0.4 mg/kg IV, IM, PO q 6 - 8 hrs
Propantheline bromide Acute colitis, ulcerative colitis, antiemetic 0.22 - 0.25 mg/kg PO q 8 hrs up to 3 days
Detrusor hyperspasticity, urge incontinence 0.2 mg/kg PO q 6 - 8hrs
Propriomazine Sedation 1.1-4.4 mg/kg IV, IM q 12 - 24hrs
Propofol General anaesthesia, status epilepticus Induction: 6 - 8 mg/kg IV stat
Induction: 2.5-4.0 mg/kg IV with premedication
Maintenance: 0.51 mg/kg IV q min
Propranolol Ventricular hypertrophy, aortic stenosis, HCM 0.4 - 1.2 mg/kg PO q 8 - 12 hrs
Ventricular arrhythmias 0.02 - 0.06 mg/kg IV over 2-3 min; q 8hrs
0.25-0.5 mg IV followed by
2.5 - 5.0 mg PO q 8hrs
hypertrophic cardiomyopathy, valvular insufficiency 2.5 mg/cat PO q 8 - 12hrs
Hypertension 2.5 - 5.0 mg/cat PO q 8 - 12 hrs
Tachyarrhythmias from endocrinopathies 2.5-5.0 mg PO q 8 - 12hrs
Propylthiouracil (PTU) Hyperthyroidism 10 mg/kg PO q 8 hrs
10 mg/kg PO q 8 - 12 hrs
Prostaglandin F2 alpha Pyometra, Cystic endometrial hyperplasia 0.10 - 0.25 mg/kg SQ q 24 hrs for 3 - 5 days
Abortion 0.5-1.0 mg/kg; 40 days post-conception SQ 2 injections 24 hrs apart
Protamine sulphate Heparin antagonist 1.0-1.5 mg for every 100 IU heparin IV stat
Pseudoephedrine Nasal decongestant 15 - 30 mg/dog PO q 8 - 12hrs
Urinary incontinence 0.2-0.4 mg/kg PO q 8 - 12hrs
Psyllium Bulk laxative 1 - 3 tsp PO q 8 - 12 hrs
Pyrantel pamoate Roundworm, hookworm 10 mg/kg PO repeat in 2 weeks
Pyridostigmine bromide Myasthenia gravis(acquired) 1-5 mg PO stat
0.25 mg/kg PO q 24hrs
Antidote (curariform) 0.15-0.30 mg/kg IM, IV
Toxoplasma 0.5-2.0 mg/kg PO q 12hrs for 14 - 28days
Enteroepithelial cycle 2 mg/kg PO q 24hrs for 14 - 28 days
Quinacrine Giardia spp, Coccidiosis 11 mg/kg PO q 24 hrs for 5 days
Ranitidine gastritis, GI tract ulceration 0.5 mg/kg IV, PO, SQ q 12 hrs
Retinol Dermatological lesions 625 - 800 IU/kg PO q 24 hrs
Rifampicin Susceptible infections 10 - 20 mg/kg PO q 24hrs
Ringer's solution Maintenance solution 40 - 50 ml/kg IV, SC, IP q 24hrs
Ronidazole (Ronivet) Tritrichomoniasis 30 mg/kg PO q 24 hrs for 14 days
(warning: low therapeutic margin) 20 mg/kg PO q 12 hrs for 14 days
Roxithromycin Susceptible infections 15 mg/kg PO q 24 hrs
Secnidazole Giardia spp 30 mg/kg PO stat
Selegiline Cognitive disorders 0.5 mg/kg PO q 24 hrs
hyperadrenocorticism 1-2 mg/kg PO q 24 hrs
Selamectin Parasiticide 6 mg/kg Topical q 30days
Selenious acid, sodium selenite Supplementation 0.3 mg/kg PO stat
Selenium Pancreatitis 0.1 mg/kg IV stat
Senna Constipation 5 ml/cat PO q 24hrs
Silver nitrate solution (0.5%) Burns Saturate wet dressing Topically q 12hrs
Sulfadiazine Burns Apply light coating Topically q 12hrs
Sodium bicarbonate Renal failure 10-15 mg/kg PO q 8hrs
Toxicoses 50 mg/kg PO q 8 - 12hrs
Hyperkalemic crisis 2-3 mEq IV over 30 mins
Urine alkalisation 0.65-5.85 g PO q 24hrs
Sodium chloride Hypoadrenocorticism 1-5 g PO q 24hrs
Hyponatremia, acute renal failure 1-4 g PO q 8hrs
(0.9% soln) 40-50 ml/kg IV, SQ, IP q 24hrs
Susceptible infections 20 mg/kg PO q 24 hrs for 4 - 6 wks
Sodium phosphate Hypercalcemia Dilute 1-3 g with water (1:1) and give 10-20 ml PO q 8 - 24hrs until stools are soft
Sodium thiopental Anaesthesia 3-15 mg/kg IV to effect
Sorafenib Chemotherapy 2 mg/kg PO once daily
Sorbitol (70% soln) Stool softener 3 ml/kg PO stat
Sotalol Ventricular arrhythmias 1-2 mg/kg PO q 12 hrs
Spectinomycin Susceptible infections 5-12 mg/kg IM q 12hrs
Spiramycin Toxoplasma spp 12.5 - 23 mg/dog PO q 24hrs
Spironolactone Diuretic: heart failure 2-4 mg/kg PO
Hyperaldosteronism 1 mg/kg PO q 12hrs
Hepatic insufficiency 3.0 - 4.0 mg/kg PO q 24 hrs
Spironolactone / hydrochlorothiazide Diuretic, antihypertensive agent 1 - 2 mg/kg PO q 12 - 24 hrs
Stanozolol Anabolic agent, anemia 1 - 2 mg/dog PO q 12 hrs
10 - 25 mg/kg PO q 7days
Staphage lysate Immune stimulant 0.1 - 0.2 ml/cat SQ then
incremental doses to 1.0ml SQ 1 - 2 for a week, then
0.5 ml SQ weekly for 10 - 12 weeks
Staphylococcal A Immune stimulant 20 µg/2.75kg</span> IP q 3 - 5 days
Streptomycin, dihydro Leptospirosis, endocarditis, Mycobacterium spp, Yersinia pestis 10 mg/kg IM q 6 hrs
Succinylcholine Paralysis 0.06 - 0.11 mg/kg IV stat
Sucralfate Gastrointestinal ulceration 250-500 mg/cat PO q 8 - 12hrs
Hemorrhagic pancreatitis, vomiting with renal failure 40 mg/kg PO q 8 hrs
Sulfadiazine Nocardiosis 220 mg/kg PO for 1 treatment, then
50-110 mg/kg PO q 12 hrs
Toxoplasmosis 15 - 50 mg/kg (with pyrimethamine) PO q 24 hrs, divided, for 14 days
Trimethoprim/Sulphonamides Susceptible infections 30 mg/kg PO, SQ q 24hrs
Meningitis 15 mg/kg PO, IV q 8 - 12 hrs
Nocardiosis 30 - 60 mg/kg PO, SQ q 12 hrs
Sulfadimethoxine Susceptible infections 25 - 50 mg/kg PO, IM, IV q 12 - 24 hrs for max of 21 days
Coccidiosis 55 mg/kg (loading), then 27.5 mg/kg PO q 24hrs
Sulfaguanidine Coccidiosis 100-200 mg/kg PO q 8hrs
Sulfamethazine, sulfamerazine Coccidiosis 200 mg/kg (loading), then 50 mg/kg PO q 12 hrs
Sulfamethoxazole Susceptible infections 100 mg/kg (loading), then 50 mg/kg PO q 12hrs
Sulfamethoxazole/Trimethoprim Susceptible infections 15 mg/kg PO q 12hrs
Sulfasalazine ulcerative colitis 250 mg/cat PO q 8hrs for 3 days, then q 24hrs
ulcerative colitis 20-25 mg/kg PO q 12 -24 hrs
Susceptible bacterial infections 20 mg/kg PO q 12hrs
Sulfisoxazole cystitis 50 mg/kg PO q 8 hrs
Sulfobromophthalein sodium Hepatic function testing 5 mg/kg IV collect serum 30 min after BSP injection
Suprofen ophthalmic Allergic conjunctivitis 1% Topically q 8 - 12 hrs
Tacrolimus Otitis externa 0.1% lotion topical q 12hrs
Telazol Restraint 6.6 mg/kg IM stat
Anesthesia 11 - 15 mg/kg IM stat
Terbinafine Fungal infections 20 - 30 mg/kg PO q 24 hrs for 4 - 10 wks
Terbutaline sulphate Bronchodilator 0.01 mg/kg SQ, IM q 4 hrs
1.25 - 2.5 mg/cat PO q 8 hrs
Testosterone cypionate Hormone replacement 2.2 mg/kg IM q 2 - 3 days
Testosterone, methyl Anabolic effects 1-2 mg/kg; max 30 mg/day PO q 24hrs
Testosterone propionate Feline symmetrical alopecia 12.5 mg with oestrogen IM stat
incontinence 5 - 10 mg IM stat
0.5 - 1.0 mg/kg IM q 2 - 3 days
Tetanus toxoid Tetanus treatment 0.2 ml (test dose), then give 100-500 units/kg SQ watch for anaphylaxis for 30 min
Tetracycline Acute bronchitis 10 - 25 mg/kg PO q 8 - 12 hrs
Rickettsia spp 15 mg/kg PO q 8 hrs for 21 days
Mycobacterium spp 22 mg/kg PO q 8hrs
Susceptible infections 1 - 5 mg/kg IV, IM q 8 - 12 hrs
Theophylline Bronchodilator 4 mg/kg PO, IM q 8 - 12 hrs
Theo-Dur (Sustained release) Bronchodilator 20 - 25 mg/kg PO q 24 hrs, at night
Thiabendazole Heartworm disease adulticide 35 mg/kg PO q 12 hrs for 20 days
Strongyloides spp 125 mg/kg PO q 24 hrs for 3 days
Thiacetarsamide Heartworm adulticide 2.2 mg/kg IV q 12 hrs for 2 days
Thiamine Thiamine deficiency 1 - 2 mg/dog IM q 12 hrs until regression of symptoms
100 - 250 mg/kg SQ q 12 hrs
Thiamylal sodium Anaesthesia 8.8 - 13.3 mg/kg IV after tranquilisation
Thioguanine Lymphocytic and granulocytic leukaemia 25 mg/m2 PO q 24hrs for 1-5 days, then 130 days
Thyroid Hypothyroidism 15 - 20 mg/kg/day PO q 24 hrs
Thiopentone General anaesthesia, status epilepticus 3 - 15 mg/kg IV to effect
Thyrotropin Provocative testing 1 IU/kg IM Collect baseline and post-TSH samples
Acanthosis nigrans, hypothyroidism 1 - 2 IU SQ q 24 hrs for 5 days
L-Thyroxine (levothyroxine) Hypothyroidism 0.5 mg/m2 PO q 12hrs
20 - 30 µg/kg</span> PO q 24 hrs
Ticarcillin Susceptible infections 33 - 50 mg/kg IM, IV q 6 - 8kg
55-110 mg/kg IM, Iv q 4 - 6hrs
Ticarcillin/clavulanate As above
Tiletamine / zolazepam Minor procedure 9.7 - 11.9 mg/kg IM stat
Castration 10.6 - 12.5 mg/kg IM do not exceed 72 mg/kg with repeat doses
Spey 14.3 - 15.8 mg/kg IM stat
Tolazoline Xylazine reversal 2 mg/kg IV stat
Tolfenamic acid Analgesia 4 mg/kg IM, SQ, PO q 24 hrs up to 5 days, 3 out of 7 days for long term Rx
Toltrazuril (Baycox) Coccidiosis 5 - 20 mg/kg PO q 24 hrs x 2 - 5 treatments
Toluene Anthelmintic 267 mg/kg PO repeat in 2 - 4 weeks
Tramadol Opioid analgesia 1 - 2 mg/kg PO q 8 - 12 hrs
12.5 mg/dog PO q 12 hrs
Triamcinolone Gingivitis, pododermatitis, acral lick granuloma 2 - 4 mg PO q 24 - 48 hrs
Pannus, episcleritis 4 mg Subconjunctival stat
Triamterene Diuretic 1 - 2 mg/kg PO q 12 hrs
Trientine hydrochloride Chelating agent 10-15 mg/kg PO q 12hrs
Triflupromazine Behaviour modification 0.1 - 0.3 mg/kg IM, PO q 8 - 12 hrs
Triiodothyronine (T3) Hypothyroidism 4.4 µg/kg PO q 8 - 12hrs
Trilostane Cushing's syndrome 30 mg/kg PO q 12 - 24 hrs
Trimethoprim/sulfadiazine Susceptible infections 15 mg/kg PO, SQ, IV q 8 - 12hrs
Tripelennamine Antihistamine 1 mg/kg PO, IM q 12 hrs
Trypan blue Babesia spp 4 mg/kg IV stat
Tylosin GI bacterial overgrowth 6.6-11 mg/kg IM q 12 - 24hrs
Chronic colitis 25 mg PO q 8hrs
Urea Osmotic 300 mg IV stat
Urokinase thromboembolism 90,000 IU over 20 minutes, then 45,000 IU CRI IV for up to 24 hrs
Urofollitropin Hypogonadotropic anovulation 2 mg/dog IM q 24hrs
Ursodeoxycholic acid chronic hepatitis 5-15 mg/kg PO q 24hrs
Valproic acid Epilepsy 25 - 65 mg/kg PO with Phenobarbital
10-105 mg/kg PO alone
Vanadium Hyperglycaemia 0.2 mg/kg PO q 24hrs
Vasopressin, aqueous Central diabetes insipidus 10 mU/cat IV, IM as needed
Vasopressin, tannate in oil Central diabetes insipidus 2.5-5.0 U/cat IM q 1- 7 days
Vecuronium bromide Paralytic agent for controlled anaesthesia 40 µg/kg IV over 30 min
Verapamil Supraventricular arrhythmias 10 - 15 mg/kg PO q 24 hrs, divided
Conversion of rapid supraventricular tachycardia 1.1-4.4 mg/kg PO q 8 - 12hrs
Vinblastine Mast cell tumour, lymphoma 0.1 - 0.4 mg/kg IV q 7 - 14 days
Vincristine Thrombocytopenia 0.01 - 0.025 mg/kg IV q 7 - 10 days
Lymphosarcoma 0.5-1.0 mg/m2 IV once weekly
Neoplasia 0.5 - 0.75 mg/m2 IV q 7 - 14 days
Viokase Exocrine pancreatic insufficiency 325 mg PO with each meal
Vitamin A Dietary supplement 400 U/kg PO q 24hrs for 10d
Vitamin B1 see Thiamine
Vitamin B2 5-10 mg/cat PO q 24hrs
Vitamin B complex Vitamin B deficiency 0.5-1.0 ml IV, IM, SQ q 24hrs
Vitamin C see Ascorbic acid
Vitamin D Hypocalcemia 0.02 mg/kg PO Initially, then
0.01 mg/kg PO q 24 - 48 hrs
Vitamin D2 (ergocalciferol) Hypocalcemia 4000 - 6000 U/kg PO q 24 hrs, initially, then
500 - 1000 U/kg PO q 24 - 48 hrs
Vitamin D3 (calcitriol - 1-25, dihydroxy vitamin D3) Hypocalcemia 0.03-0.06 µg/kg PO q 24 hrs
Chronic renal disease 0.025 µg/kg PO q 24 hrs
Vitamin E myopathy, myocarditis, retinal pigment epithelial dystrophy 10 - 20 IU/kg PO q 12 hrs
Pemphigus 400 - 600 IU/dog PO q 12 hrs
Vitamin K1 Deficiency, hepatopathy 1 - 3mg/kg SQ, PO q 12 hrs for 4 - 6 weeks
5mg/kg PO q 24hrs, divided doses
Warfarin thromboembolism 0.06 - 0.20 mg/kg PO q 24 hrs. Maintain PTT at 2 - 2.5 times normal
Xylazine Muscle relaxation 1.1 - 2.2mg/kg IM, SQ stat
Emetic 0.44mg/kg IM
Zafirlukast Leukotriene receptor antagonist 0.15 - 0.2mg/kg PO q 12 - 24 hrs
Zinc Antioxidant 2 - 3 mg/kg PO q 24 hrs
Zonisamide Epilepsy 5 mg/kg PO q 12 hours