Vasopressin (Antidiuretic hormone - ADH; Desmopressin) is a critical hormone in the regulation of water balance and appetite, effected upon the renal tubules. Its function is similar to angiotensin upon water retention.
Vasopressin is secreted from the posterior pituitary gland in response to reductions in plasma volume, in response to increases in the plasma osmolality, and in response to cholecystokinin secreted by the small intestine. It results in water and sodium resorption. In higher doses, it also causes hyponatremia and vasocontriction, resulting in hypertension and has been used in the treatment of syndrome of inappropriate antidiuretic hormone .
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