From Cow

Acorea is a rare autosomal recessive congenital eye disease of calves worldwide[1].

This disease is characterised by calves born without an iris[2]. This disease may be unilateral or bilateral[3].

Affected calves are often culled due to worsening visual loss.

Other congenital diseases such as microphthalmos, microcoria, microcornea, microlentia, cataracts, retinal dysplasia, retinal detachment and proliferation of the anterior neuroectoderm[4].


  1. Abbasi AR et al (2009) A mutation of the WFDC1 gene is responsible for multiple ocular defects in cattle. Genomics 94(1):55-62
  2. Kaswan RL et al (1987) Multiple hereditary ocular anomalies in a herd of cattle. J Am Vet Med Assoc 191(1):97-99
  3. Hurley S (2008) Blind but healthy calves. Vet Rec 163(19):579
  4. Rupp GP & Knight AP (1984) Congenital ocular defects in a crossbred beef herd. J Am Vet Med Assoc 184(9):1149-1150