Doramectin

From Cow
Doramectin01.jpg

Doramectin is a synthetic avermectin shown to be effective against internal and external parasites of cattle[1].

It is a macrocyclic lactone effective against gastrointestinal nematodes, lungworms, eyeworms, warbles, lice, ticks, mange mites and dung beetles[2]. It appears equally efficacious as ivermectin and moxidectin[3].

Doramectin is available as an oral or injectable formulation.

Recommended dose is 200-500 μg/kg body weight given by subcutaneous injection.

Sensitivity to avermectin B1 was reported in Murray Grey cattle.

References

  1. Davey RB et al (2012) Analysis of doramectin in the serum of repeatedly treated pastured cattle used to predict the probability of cattle fever ticks (Acari: Ixodidae) feeding to repletion. Exp Appl Acarol 56(4):365-374
  2. Webb L et al (2010) Field-scale dispersal of Aphodius dung beetles (Coleoptera: Scarabaeidae) in response to avermectin treatments on pastured cattle. Bull Entomol Res 100(2):175-183
  3. Avcioglu H & Balkaya I (2011) A comparison of the efficacy of subcutaneously administered ivermectin, doramectin, and moxidectin against naturally infected Toxocara vitulorum in calves. Trop Anim Health Prod 43(6):1097-1099