This disease is characterised by partial or complete absence of hair follicles, with or without associated developmental defects such as color dilution, congenital hypotrichosis and anodontia (HAD), and congenital hypotrichosis and incisor anodontia (HID).
Affected cattle show abnormalities in hair follicles, keratinocytes, sweat glands, and teeth. However, a hypo-trichotic Holstein bull has presented with respiratory lesions, suggesting that deficiencies in epithelial mucosal secretions may be associated with this disease.
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