The single-stranded RNA molecule that encodes five viral proteins: polymerase L, matrix protein M, phosphoprotein P, nucleoprotein N, and glycoprotein G, which form a separate monophyletic lineage consisting of sub-lineages A and B. Genetic markers on the Lyssavirus indicates a possible variation between geographic regions, although the biologically active regions are conserved.
In cattle, Lyssaviral antigens are most prominent in the brainstem, followed by the cerebellum.
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