Non-steroidal anti-inflammatory agents (NSAIDs) are a class of drugs commonly used in bovine medicine for treatment of a wide range of conditions such as mastitis, puerperal metritis, cancer and perioperative analgesia.
NSAIDs provide a cost-effective and convenient strategy for analgesia, however, the judicious use of NSAIDs must include a balance between relief of symptoms and side effects.
The most common NSAID-associated toxicities include renal toxicity and gastrointestinal ulceration. Other less common but potentially life-threatening side effects include hepatotoxicity, platelet dysfunction and bleeding, aplastic anemia, delayed bone healing and increased cartilage degradation.
Commonly used NSAIDs in bovine practise include: