From Cow
Foot rot in a cow which responded to penicillin therapy

Penicillin is a broad-spectrum antimicrobial drug effective against most Gram-positive and some Gram-negative bacteria.

All penicillins are ineffective toward cell wall-deficient microorganisms such as Mycoplasma spp or Chlamydophila spp[1].

Included in the penicillins are:

  • Penicillin G, penicillin V and phenethicillin - Staphylococcus spp, Streptococcus spp
  • Oxacillin, cloxacillin, dicloxacillin, flucloxacillin, methicillin, temocillin and nafcillin - Gram positive and most Gram-negative bacteria except Pseudomonas spp
  • Ampicillin, amoxicillin, hetacillin, pivampicillin, talampicillin and mecillinam - most Gram-positive and Gram-negative
  • Carbenicill, inazlocillin, mezlocillin, piperacillin and ticarcillin - most Gram-positive and Gram-negative bacteria, including Pseudomonas aeruginosa, Proteus spp and Klebsiella spp
  • Imipenem and meropenem - most Gram-positive and Gram-negative bacteria

Ampicillin and amoxycillin are the most frequently used in bovine medicine for diseases such as:

Penicillins are effective against: