Peste des petits ruminants

From Cow
Electron microscopic view of a morbillivirus

Peste des petits ruminants (PPR; 'goat plague') is a notifiable viral disease of cattle[1].

This disease is caused by a morbillivirus (f. Paramyxoviridae).

Cattle are usually infected asymptomatically and are exposed to PPR infection naturally[2]. The transmission mode to other ruminants may be direct or indirect, and cattle may play a role as subclinical hosts for the virus[3].

Diagnosis is most accurately determined based on presenting clinical signs supported with evidence of viral presence using ELISA[4] or PCR assay analysis of infected samples.

The disease must be distinguished from other causes of stomatitis including bovine mucosal disease, malignant catarrhal fever, rinderpest, foot and mouth disease, contagious ecthyma, blue tongue, epizootic haemorrhagic disease, papular stomatitis and vesicular stomatitis[5].

It should be noted that cattle which have been exposed to the PPR virus show poor responses to live attenuated Rinderpest vaccine[6].


  1. Liu FX et al (2012) Feasibility study on global peste des petits ruminants eradication based on rinderpest eradication. Bing Du Xue Bao 28(1):89-96
  2. Khan HA et al (2008) The detection of antibody against peste des petits ruminants virus in sheep, goats, cattle and buffaloes. Trop Anim Health Prod 40(7):521-527
  3. Balamurugan V et al (2012) Seroprevalence of Peste des petits ruminants in cattle and buffaloes from Southern Peninsular India. Trop Anim Health Prod 44(2):301-306
  4. Albayrak H & Gür S (2010) A serologic investigation for Peste des petits ruminants infection in sheep, cattle and camels (Camelus dromedarius) in Aydin province, West Anatolia. Trop Anim Health Prod 42(2):151-153
  5. Merck Vet Manual
  6. Couacy-Hymann E et al (2006) Interference in the vaccination of cattle against rinderpest virus by antibodies against peste des petits ruminants (PPR) virus. Vaccine 24(29-30):5679-5683