Retinal dysplasia

From Cow
Retinal dysplasia in a calf with Neuropathic hydrocephalus[1]

Retinal dysplasia is a rare autosomal recessive congenital eye disease of calves worldwide[2].

This disease is characterised by calves born with impaired acuity due to retinal disease[3]. This disease may be unilateral or bilateral[4].

In cattle, retinal dysplasia cause blindness and affected calves require either corrective surgery or are culled[5].

This disease has been seen associated with bovine viral diarrhea infection[6].

Other congenital diseases such as microphthalmos, microcoria, microcornea, microlentia, cataracts, retinal detachment, anterior segment dysgenesis, acorea and proliferation of the anterior neuroectoderm[7].


  1. Leipold HW et al (1974) Retinal dysplasia and internal hydrocephalus in a shorthorn calf. Can Vet J 15(2):34-38
  2. Abbasi AR et al (2009) A mutation of the WFDC1 gene is responsible for multiple ocular defects in cattle. Genomics 94(1):55-62
  3. Kaswan RL et al (1987) Multiple hereditary ocular anomalies in a herd of cattle. J Am Vet Med Assoc 191(1):97-99
  4. Hurley S (2008) Blind but healthy calves. Vet Rec 163(19):579
  5. Uchida K et al (2006) Congenital multiple ocular defects with falciform retinal folds among Japanese black cattle. Vet Pathol 43(6):1017-1021
  6. Roeder PL et al (1986) Pestivirus fetopathogenicity in cattle: changing sequelae with fetal maturation. Vet Rec 118(2):44-48
  7. Rupp GP & Knight AP (1984) Congenital ocular defects in a crossbred beef herd. J Am Vet Med Assoc 184(9):1149-1150