Alkaline phosphatase

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Alkaline phophatase (AP) is widely distributed in canine tissue.

Levels of AP can rise as a reflection of rapid growth of bone associated with juvenile dogs, with osteosarcoma, hyperparathyroidism and due to cholestasis with bile duct carcinoma or hepatic carcinoma.

It is an enzyme that is routinely tested during serum biochemical analysis of blood samples.

By itself, a diagnosis cannot be achieved and interpretation of other biochemical enzymes must be assessed such as ALT, ALP and ionized calcium.