AST

From Dog

Aspartate transaminase (AST) is a liver function test routinely performed on most biochemical blood tests on dogs.

AST, which converts aspartate and α-ketoglutarate to oxaloacetate and glutamate, is produced in the liver, heart, skeletal muscle, kidneys, brain, and red blood cells.

AST is not as accurate in determining liver disease than ALT, which is predominantly produced by liver parenchymal cells.

AST can be elevated with underlying diseases such as hepatitis, congenital hepatic fibrosis and portosystemic shunt.

Normal levels are 8.9 - 49 U/L.