Acarbose

From Dog
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Acarbose is an α-glucosidase inhibitor used as an anti-diabetic drug used to treat canine diabetes mellitus[1].

This oral medication appears to have reasonable efficacy at reducing hyperglycemia in dogs[2], with efficacy similar to metformin.

Few side-effects have been reported with this medication[3] and the recommended dose rate in dogs is 25 - 50 mg orally once daily[4].

References

  1. Hollander P (1982) Safety profile of acarbose, an alpha-glucosidase inhibitor. Drugs 44 (3):47-53
  2. Nelson RW (2000) Oral medications for treating diabetes mellitus in dogs and cats. J Small Anim Pract 41(11):486-490
  3. Robertson J et al (1999) Effects of the alpha-glucosidase inhibitor acarbose on postprandial serum glucose and insulin concentrations in healthy dogs. Am J Vet Res 60(5):541-545
  4. Nelson RW et al (2000) Effect of the alpha-glucosidase inhibitor acarbose on control of glycemia in dogs with naturally acquired diabetes mellitus. J Am Vet Med Assoc 216(8):1265-1269