Acitretin
From Dog
Acitretin is a second-generation retinoid that is a metabolite of etretinate, and a safer product for use in canine skin diseases[1].
Acitretin seems to act rather as a substrate in dermatological disease repair than an enzymatic inducer[2].
This retinoid has been used successfully in spiculosis.
Recommended dose in dogs is 0.5 - 2.0 mg/kg every 24 hrs orally.