Alprazolam is a benzodiazepine anxiolytic drug which acts at the limbic, thalamic, and hypothalamic level of the CNS and has anxioytic, sedative, hypnotic, skeletal muscle relaxant, and anticonvulsant properties.
Toxicity has been reported following accidental consumption of large doses.
Symptoms of toxicosis include ataxia, depression, vomiting, tremors, tachycardia, diarrhea and ptyalism, usually within 30 minutes of ingestion.
Treatment included standard decontamination procedures, such as induction of emesis with apomorphine and gastric lavage with activated charcoal.
Recommended dose rate in dogs is 0.02 mg/kg given orally every 12 hrs.
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