From Dog

Amitraz is an organophosphate insecticide used as a preventative against ticks.

This chemical is effective at both insecticidal and residual protection against ticks, fleas and other external parasites such as Demodex spp[1].

Atipamezole effectively counteracts the clinical effects of amitraz toxicity, and appears more effective than other drugs such as yohimbine[2].


  1. Kuznetsova E et al (2012) Influence of systemic antibiotics on the treatment of dogs with generalized demodicosis. Vet Parasitol 188(1-2):148-155
  2. Andrade SF &Sakate M (2003) The comparative efficacy of yohimbine and atipamezole to treat amitraz intoxication in dogs. Vet Hum Toxicol 45(3):124-127