Amoxycillin/clavulanate is one of the more popular broad-spectrum antimicrobial compounds used in veterinary medicine.
This drug, which is a compounded combination of amoxicillin and clavulanic acid augments the effects of amoxycillin.
This combination has been shown to be effective in treating a wide range of diseases of dogs including: skin disease (including deep and superficial pyoderma), cystitis, prostatitis, pneumonia and enteritis.
The clavulanate in this product counteracts this defence mechanism by inactivating the ß-lactamases, thus rendering the organisms sensitive to the rapid bactericidal effect of amoxycillin at concentrations readily attainable in the body.
In vitro, amoxycillin/clavulanate is active against a wide range of clinically important bacteria including:
- Staphylococcus spp (including ß-lactamase producing strains)
- Corynebacterium spp
- Streptococcus spp
- Escherichia coli (including ß-lactamase producing strains)
- Salmonella spp (including ß-lactamase producing strains)
- Bordetella bronchiseptica
- Pasteurella spp
- Proteus mirabilis
- Klebsiella spp
This product is not indicated for cases involving Pseudomonas spp.