Anaphylaxis

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Anaphylaxis is defined as an acute allergic response, resulting in release of histaminergic compounds.

This leads to rapid hypovolemia, hypotension and circulatory shock.

Anaphylaxis can involve several organ systems, particularly the skin, respiratory tract, gastrointestinal tract and the cardiovascular system. The severity of anaphylactic reaction is variable and can be classified into severity grades I - IV. Some anaphylactoid reactions can be fatal in dogs.

Causes include:

References

  1. Souney PF (2009) Re: Adverse effects of intravenous amiodarone in 5 dogs. J Vet Intern Med 23(6):1127
  2. Girard NM & Leece EA (2010) Suspected anaphylactoid reaction following intravenous administration of a gadolinium-based contrast agent in three dogs undergoing magnetic resonance imaging. Vet Anaesth Analg 37(4):352-356
  3. Thomas E et al (2013) Survival After Anaphylaxis Induced by a Bumblebee Sting in a Dog. J Am Anim Hosp Assoc Mar 27
  4. Mandigers P & German AJ (2010) Dietary hypersensitivity in cats and dogs. Tijdschr Diergeneeskd 135(19):706-710
  5. Parra LE et al (2007) Safety trial using the Leishmune vaccine against canine visceral leishmaniasis in Brazil. Vaccine 25(12)':2180-2186
  6. Moore GE et al (2005) Adverse events diagnosed within three days of vaccine administration in dogs. J Am Vet Med Assoc 227(7):1102-1108