Total serum bile acids are liver enzymes used for detection of various diseases in dogs such as cholangiohepatitis, portosystemic shunts, inflammatory bowel disease, pancreatitis and hyperadrenocorticism.
Measurements are usually performed before and 2 hr after meal ingestion with pre- and post-prandial ranges 0-10 and 0-20 μM/L respectively.
Insufficient hepatic processing of bile acids due to underlining diseases cause high bile acid levels and concentrations >25 μM/L should be considered abnormal either before or after a meal.
It should be noted that administration of glucocorticoids results in lower readings in dogs.
Liver biopsies are usually performed in suspicious cases.
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