Cabergoline is a potent dopamine D2-receptor agonist, acting on on pituitary lactotroph (prolactin) cells.
Side-effects include milk loss post-partum.
Recommended dose for estrus induction is 10 - 20 IU/kg/day intramuscularly for 5 consecutive days, followed by an additional single injection of 25 IU/kg of human chorionic gonadotrophin on the fifth day.
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- Nak D et al (2012) Comparison of the use of cabergoline and gonadotrophin to treat primary and secondary anoestrus in bitches. Aust Vet J 90(5):194-196
- Romagnoli S et al (2009) Effect of an injectable cabergoline formulation on serum prolactin (PRL) and milk secretion in early postpartum Beagle bitches. Reprod Domest Anim 44(2):148-151