Captopril

From Dog

Captopril is an ACE-inhibitor which causes peripheral vasodilation, and is used for treatment of canine hypertension and congestive heart failure.

Captopril has been shown to markedly improved renal arterial blood supply in dogs with renal hypertension[1].

Side effects such as aplastic pancytopenia have been reported[2].

Recommended dose rate in dogs is 2 - 3 mg given orally every 8 - 12 hours.

References

  1. Miyajima T et al (2005) Quantitative estimation of renal blood flow by power Doppler ultrasonography in renovascular hypertensive dogs. Kidney Int 68(6):2781-2786
  2. Weiss DJ & Klausner JS (1990) Drug-associated aplastic anemia in dogs: Eight cases (1984–1988). J Am Vet Med Assoc 196:472–475