In canine medicine, it is commonly used for treatment of iron toxicity associated with ingestion of moisture/oxygen absorbers (package inserts) and commercial snail and slug bait containing iron EDTA.
Chelation therapy with desferrioxamine mesylate causes few adverse effects when given at recommended doses.
Recommended dose rate in dogs is 10 mg/kg given parenterally every 2 hours for 2 doses then every 8 hours for 24 hours.
- Davis S et al (1997) Parallel antioxidant and antiexcitotoxic therapy improves outcome after incomplete global cerebral ischemia in dogs. Stroke 28(1):198-204
- Groebler LK et al (2011) Comparing the potential renal protective activity of desferrioxamine B and the novel chelator desferrioxamine B-N-(3-hydroxyadamant-1-yl)carboxamide in a cell model of myoglobinuria. Biochem J 435(3):669-677
- Brutlag AG et al (2012) Iron intoxication in a dog consequent to the ingestion of oxygen absorber sachets in pet treat packaging. J Med Toxicol 8(1):76-79
- Haldane SL & Davis RM (2009) Acute toxicity in five dogs after ingestion of a commercial snail and slug bait containing iron EDTA. Aust Vet J 87(7):284-286