Deracoxib

From Dog

Deracoxib (Deramaxx) is a nonsteroidal anti-inflammatory drug, similar in activity to meloxicam and carprofen, and is used in canine medicine for treatment of osteoarthritis and post-operative pain management[1].

This drug is also used for management of transitional cell carcinoma[2].

Long-term use at high doses may result in platelet dysfunction[3] and erosive ulceration leading to gastritis and duodenitis[4].

Recommended dose rate is 3 mg/kg as a single dose for post-operative pain, and 1 - 2 mg/kg for a maximum of 7 days[5].

References

  1. Bienhoff SE et al (2012) Efficacy and safety of deracoxib for control of postoperative pain and inflammation associated with soft tissue surgery in dogs. Vet Surg 41(3):336-344
  2. McMillan SK et al (2011) Antitumor effects of deracoxib treatment in 26 dogs with transitional cell carcinoma of the urinary bladder. J Am Vet Med Assoc 239(8):1084-1089
  3. Mullins KB et al (2012) Effects of carprofen, meloxicam and deracoxib on platelet function in dogs. Vet Anaesth Analg 39(2):206-217
  4. Case JB et al (2010) Proximal duodenal perforation in three dogs following deracoxib administration. J Am Anim Hosp Assoc 46(4):255-8
  5. Novartis