Dexamethasone

From Dog

Dexamethasone is a potent medium-acting anti-inflammatory and immunosuppressant corticosteroid used extensively in dogs.

Dexamethasone is a synthetic analogue of prednisolone, having similar but more potent anti-inflammatory therapeutic action and diversified hormonal and metabolic effects.

In dogs, this drug is used in acute inflammatory conditions, including shock[1], glucocorticoid crisis associated with hypoadrenocorticism and polyneuropathies[2].

Recommended dose rate in dogs is 0.1 - 5.0 mg/kg given as a single dose.

References

  1. Hicks CW et al (2012) Efficacy of selective mineralocorticoid and glucocorticoid agonists in canine septic shock. Crit Care Med 40(1):199-207
  2. Gorson KC (2010) A new trick for an old dog: pulsed dexamethasone treatment for chronic inflammatory demyelinating polyneuropathy. Lancet Neurol 9(3):228-229