Difloxacin hydrochloride is a broad-spectrum fluoroquinolone antimicrobial drug active against Gram-positive and Gram-negative bacteria, but with less potency than enrofloxacin or pradofloxacin.
Difloxacin inhibits bacterial DNA gyrase and the topoisomerase II enzyme, which inhibits DNA replication and transcription.
Recommended dose rate in dogs is 5 - 10 mg/kg given orally every 24 hours.
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