Dinoprost

From Dog

Dinoprost (PGF) is a synthetic prostaglandin used as an abortifacient in conjunction with aglepristone[1].

Prostaglandin is produced endogenously in bitches during induction of labor and higher levels in association with reduced oxytocin and vasopressin are associated with primary uterine inertia[2].

References

  1. Gogny A et al (2010) In vitro comparison of myometrial contractility induced by aglepristone-oxytocin and aglepristone-PGF2alpha combinations at different stages of the estrus cycle in the bitch. Theriogenology 74(9):1531-1538
  2. Bergström A et al (2010) Hormonal concentrations in bitches with primary uterine inertia. Theriogenology 73(8):1068-1075